A rare case of super giant basal cell carcinoma

Desmond, Bryce; Boudreaux, Lauren; Young, J. M.

doi:10.1016/j.jdcr.2015.06.004

Cited by 13 publications

(21 citation statements)

References 7 publications

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“…1 Literature review found only 11 cases reported. 2,3 In contrast to BCCs, which are often found in the sun-exposed areas of the head and neck, GBCCs are located predominantly on the back, where they go unnoticed by the patient and can remain hidden under clothing. 4 There is a greater propensity for metastasis, particularly after reaching a size of 10 cm.…”

Section: Discussionmentioning

confidence: 99%

Super giant basal cell carcinoma in an autistic patient: A case report

Hudson

Hilal

2020

SAGE Open Medical Case Reports

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Basal cell carcinoma is the most common skin cancer in the world and is generally treated when small in size with an excellent prognosis. Rarely, basal cell carcinoma will grow to be larger than 5 cm, at which point they are termed giant basal cell carcinoma. Giant basal cell carcinoma comprises only 0.5% of all basal cell carcinoma, but is associated with impaired quality of life and increased risk of metastasis. When a basal cell carcinoma grows to over 20 cm in size, it is termed super giant basal cell carcinoma. Here, we report a case of both a super-giant basal cell carcinoma and a giant basal cell carcinoma developing over 10–12 years on the upper back and anterior chest wall of an autistic male. Generally, this presentation is associated with neglect on the part of the patient. This case report demonstrates a super-giant basal cell carcinoma developing secondary to patient neglect in the context of comorbid mental illness.

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Section: Discussionmentioning

confidence: 99%

Super giant basal cell carcinoma in an autistic patient: A case report

Hudson

Hilal

2020

SAGE Open Medical Case Reports

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“…Wide local excision of the lesion with histologically confirmed negative margins with a reconstruction of the defect followed by adjuvant chemoradiation gives a better outcome compared to radiotherapy or chemotherapy alone [6]. The NCCN recommends standard excision (SE) with more than 6-mm peripheral margins for high-risk BCC, while the European Dermatology Forum (EDF) and Cancer Council Australia, and Australian Cancer Network recommend SE using up to 10-mm peripheral margins [7].…”

Section: Discussionmentioning

confidence: 99%

Giant Ulcerative Basal Cell Carcinoma with Local Metastasis: A Case Report and Assessment of Surgical Techniques

Sahned¹,

Saeed

Misra³

et al. 2019

Cureus

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Giant basal cell carcinoma (GBCC) is a rare skin cancer characterized by an aggressive biological behavior with extensive local invasion, frequent metastasis, and associated poor prognosis. Wide local excision with sentinel lymph node biopsy is often warranted for this condition, and reconstruction by local rotational flap is one of the best surgical techniques for repairing similar skin cancers with a relatively large skin defect. A 59-year-old man who was a former construction worker with a significant smoking history presented with a single giant suspicious chronic ulcerating skin lesion measuring 9 x 7 cm that proved to be a basal cell carcinoma (BCC) on his left shoulder. The patient was negative for enlarged or palpable lymph nodes and underwent a wide local excision and primary repair with a local flap. Despite negative margins, his follow-up visits at six, nine, and 10 months revealed numerous suspicious lesions that further required multiple local wide excisions that showed new basal cell carcinoma and recurrence to the left axilla. Given the invasiveness of his skin cancer, he was referred to oncology and later treated by chemoradiation. Patients with multiple risk factors are associated with a higher incidence of more invasive skin cancer due to possible cumulative effects. The therapeutic approach for GBCC should involve multidisciplinary teams, with wide local resection of the tumor with possible sentinel lymph node biopsy, local rotational flap for reconstruction of the wide defect, and adjuvant chemoradiotherapy if necessary.

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“…Previous case reports of multiple GBCCs also described patients with established beliefs in holistic or religious treatments [3, 5, 8]. In some instances, patients that experienced BCC recurrence after surgical excision were frustrated by the outcome and rejected all further care, leading to progression and death from associated complications [10]. …”

Section: Discussionmentioning

confidence: 99%

Giant Basal Cell Carcinomas Arising on the Bilateral Forearms of a Patient: A Case Report and Review of Nonsurgical Treatment Options

et al. 2016

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Giant basal cell carcinomas (GBCCs) are large basal cell carcinomas (BCCs; <5 cm) with a greater propensity to invade and metastasize than standard BCCs. The presence of 2 GBCCs in a single individual is rare. We present the case of a 71-year-old Caucasian male with bilateral GBCCs on the dorsal forearms, measuring 130 cm² and 24 cm², respectively, that developed over a 21-year period. Over this period, the patient treated the tumors with herbal remedies. Histologic evaluation showed a conventional nodular BCC for both tumors. Computed tomography and magnetic resonance imaging revealed a T4N0M0 stage for the larger lesion. Surgical excision and grafting and reconstruction were offered, but he declined. This case highlights a shared belief in holistic treatments and rejection of Western medical interventions that are common among many patients with GBCC. Studies reporting nonsurgical treatments for GBCCs, including radiotherapy, vismodegib, topical imiquimod, and acitretin are reviewed.

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A rare case of super giant basal cell carcinoma

Cited by 13 publications

References 7 publications

Super giant basal cell carcinoma in an autistic patient: A case report

Super giant basal cell carcinoma in an autistic patient: A case report

Giant Ulcerative Basal Cell Carcinoma with Local Metastasis: A Case Report and Assessment of Surgical Techniques

Giant Basal Cell Carcinomas Arising on the Bilateral Forearms of a Patient: A Case Report and Review of Nonsurgical Treatment Options

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