A Rare Case Report of Skin Metastasis in Gastric Cancer

Şahin, Mustafa Turhan; Ekinci, Ferhat; Çelik, Çiğdem; Temız, Peyker; Erdoğan, Atike Pınar

doi:10.1007/s12029-021-00603-3

Cited by 5 publications

(6 citation statements)

References 13 publications

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“…The most commonly affected body surface areas are the neck, back, and abdomen, although the face can be involved. 7 Grossly, these lesions appear as singular or grouped nodules, often with erythematous bases. Less commonly, as in our case, lesions may resemble skin and soft tissue infections (eg, cellulitis and erysipelas), leading some patients to be inappropriately treated with antibiotics.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Cutaneous Gastric Adenocarcinoma With Signet Ring Cell Features

Garcia,

Maqsudlu,

Dhawan

et al. 2024

ACG Case Rep J

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Cutaneous metastatic disease from primary gastric cancer is quite scarce, often going unrecognized. In this case, the patient presented with an expanding rash that was biopsied, with findings concerning for metastatic adenocarcinoma from a suspected luminal upper gastrointestinal origin. Subsequent biopsies during an esophagogastroduodenoscopy confirmed poorly differentiated adenocarcinoma with signet ring cell features, most likely from an upper gastrointestinal primary (gastric vs gastroesophageal junction). We review this case to help providers identify signet cell type cutaneous metastases of gastric cancer quickly to improve patient outcomes.

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Section: Discussionmentioning

confidence: 99%

A Rare Case of Cutaneous Gastric Adenocarcinoma With Signet Ring Cell Features

Garcia,

Maqsudlu,

Dhawan

et al. 2024

ACG Case Rep J

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“…Cutaneous metastases of GC mainly manifest as nodules or masses[ 1 , 5 , 10 , 11 ]. Less frequently, they appear like sclerodermoid or inflammatory lesions[ 2 , 3 , 4 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

“…Cutaneous metastasis usually occurs in the late stage but sometimes appears as the first manifestation[ 5 - 9 ]. Single or multiple nodules are the most common clinical presentations[ 1 , 2 , 5 - 7 , 10 - 12 ]. In this paper, we report a patient with GC who developed cutaneous metastases with extensive redness and swelling, followed by skin thickening and nodules.…”

Section: Introductionmentioning

confidence: 99%

Inflammatory cutaneous metastases originating from gastric cancer: A case report

Tian,

Ye,

et al. 2023

World J Clin Cases

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BACKGROUND Cutaneous metastasis with gastric cancer (GC) origin is extremely rare and associated with poor prognosis. Nodular type is the most common type, while other forms are extremely rare. CASE SUMMARY This study describes severe skin redness, swelling, pain, and fever in a 65-year-old man diagnosed with GC, whose left chest wall, left upper limb, and left back were mainly affected. Firstly, the patient was diagnosed with “lymphangitis” and treated to promote lymphatic return. However, the symptoms were constantly deteriorating, and skin thickening and scattered small nodules gradually appeared. Finally, the skin biopsy confirmed cutaneous metastases, and the patient died 7 d later. CONCLUSION Our case highlights that cutaneous metastasis should be considered when skin lesions appear in patients with GC.

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“…The most common metastatic sites include the neck, the back, the abdomen, and the inguinal region; the lesions may evolve as single or multiple nodules with an erysipelas-like morphology (also confirmed in our patient). Gender-wise, men have been suggested to have a higher risk for developing skin metastases (18).…”

Section: Discussionmentioning

confidence: 99%

“…In cases of cutaneous metastasis originating from primary gastric cancer, the prognosis is poor. In six out of the ten described case reports, the survival time after diagnosis of skin metastases was reported to be between 1-16 months (18). Treatment plans vary depending on the extent of the cutaneous lesions and the systemic disease, as well as the performance status of the patient; they usually include local excision, irradiation, or systemic chemotherapy.…”

Section: Discussionmentioning

confidence: 99%

Skin metastases from gastric cancer, a rare entity masquerading as erysipelas: A case report

et al. 2022

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Gastric cancer (GC) is the fifth most commonly diagnosed malignancy and the fourth leading cause of cancer death worldwide. Skin metastases from internal organs are rare; skin metastasis from GC occurs even more rarely than skin metastases originating from other organs, and is associated with systematic disease and poor prognosis. The present study described an interesting and rare case of an extensive skin rash in a 42-year-old man diagnosed with GC, which was mainly affecting his left hemithorax, abdomen and back. The rash masqueraded as erysipelas and was initially treated as such; however, it did not respond to antibiotics, corticosteroids and antihistamines. Due to its persistence and location, the rash was biopsied and GC metastasis was confirmed. Thirdline chemotherapy was administered and the rash decreased in size; however, the patient suffered from disease deterioration with lung metastases and respiratory failure. The patient eventually died 4 months after the diagnosis of skin metastasis. In conclusion, cutaneous metastasis should be considered as a late and difficult to treat metastasis of GC, which requires high surveillance from medical oncologists, and a multidisciplinary approach for prompt and accurate diagnosis.

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A Rare Case Report of Skin Metastasis in Gastric Cancer

Cited by 5 publications

References 13 publications

A Rare Case of Cutaneous Gastric Adenocarcinoma With Signet Ring Cell Features

A Rare Case of Cutaneous Gastric Adenocarcinoma With Signet Ring Cell Features

Inflammatory cutaneous metastases originating from gastric cancer: A case report

Skin metastases from gastric cancer, a rare entity masquerading as erysipelas: A case report

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