2021
DOI: 10.1177/23247096211029751
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A Rare Case Report of a Corpus Callosal Splenial Lesion in the Context of Atypical Neuroleptic Malignant Syndrome

Abstract: In this report, we describe a case of atypical neuroleptic malignant syndrome (NMS) presenting with an isolated lesion in the splenium of the corpus callosum (ILSCC). There is a paucity of information regarding this topic within the literature and only 7 previous case reports have been published at the time of writing. To our knowledge, this case report is also the first to describe an atypical NMS variant in the context of an ILSCC. In this report, we describe the important considerations in formulating diffe… Show more

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Cited by 2 publications
(1 citation statement)
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References 23 publications
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“… 20–22 However, it remains unclear whether anticholinergic agents exacerbate hyperthermia in NMS. Furthermore, in recent years, benztropine has reportedly been effective against NMS, 23 and biperiden and bromocriptine have been effective against NMS. 24 Dysphagia and sialorrhea are observed in many NMS patients, and both symptoms can trigger aspiration pneumonia associated with the risk of death.…”
Section: Discussionmentioning
confidence: 99%
“… 20–22 However, it remains unclear whether anticholinergic agents exacerbate hyperthermia in NMS. Furthermore, in recent years, benztropine has reportedly been effective against NMS, 23 and biperiden and bromocriptine have been effective against NMS. 24 Dysphagia and sialorrhea are observed in many NMS patients, and both symptoms can trigger aspiration pneumonia associated with the risk of death.…”
Section: Discussionmentioning
confidence: 99%