A rare complication of a hemodialysis tunneled catheter: Case report of a superior vena cava and right atrium candida endocarditis

Sousa, Mariana; Martins, Joana; Barreto, Sara; Santos, Cristina; Gouveia, Rita; Santos, José; Guerra, Nuno; Ramos, Aura

doi:10.1016/j.idcr.2020.e00768

Cited by 2 publications

(3 citation statements)

References 11 publications

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“…In 86 reports, 91 cases of definitive fungal IE were described. These reports involved fifteen cases with Candida parapsilosis [40][41][42][43][44][45][46][47][48][49][50][51][52][53][54] , seven cases with C. albicans [55][56][57][58][59][60][61] , three cases with C. tropicalis [62][63][64] , eight other species with Candida [65][66][67][68][69][70][71][72] , eight cases with Candida with a bacterium [73][74][75][76][77][78][79][80] , ten cases with Aspergillus fumigatus [81][82][83][84][85][86][87][88][89]…”

Section: Case Reportsmentioning

confidence: 99%

“…Quantitative polymerase chain reaction (qPCR) with genetic sequencing was performed in only one patient with Candida infection [71] , three with Aspergillus infection [81,92,95] , and for several other microorganisms [112,117,122,124,125] . To document and, if necessary, treat ocular involvement, an ophthalmic examination was performed in ten patients with Candida infection [45,49,52,56,57,59,62,63,76,78] , five patients with Aspergillus [81,87,88,93,97] , and three patients with other species [113,114,124] .…”

Section: Case Reportsmentioning

confidence: 99%

“…Third, immune compromised conditions [71,83,107,120] , such as post-splenectomy [82] organ transplantation or malignancy [45,85,100,[112][113][114]117,122,125] , or need for steroids for other reasons [16,46,81,93] , also offer an indication. However, some immunocompetent patients could suffer from fungal IE [121] and risk factors may either be absent [99,101] or restricted to an indwelling urinary catheter [59,67] . Fourth, other clues can be IV drug use [40,55,57,61,66,73,74,92] , hemodialysis [16,94] , an earlier IE [56,61] , or extended treatment by antibiotics for other reasons [54,70,86,101] .…”

Section: Signs and Symptoms Of Fungal Iementioning

confidence: 99%

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“Not much room for mushrooms” in the heart: knowns and unknowns of fungal infective endocarditis

Mistiaen

2024

Vessel Plus

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Fungal infective endocarditis is a rare but highly lethal condition. Its diagnosis is often delayed due to nonspecific symptoms, inconclusive medical imaging, and negative blood cultures. Recent reviews of cases and series over the last 5 years indicate that the condition remains rare and lethal. If fungi are identified as the causative agents in more than 5% of patient cases with infective endocarditis, it is likely that risk factors such as immune suppression or cardiac implants are probably involved. A series derived from recent case reports indicates that Candida and Aspergillus are still the main causative infectious agents, with. C parapsilosis on the rise. From these cases, diagnostic clues (frequent embolisms, ophthalmic involvement, large, mobile and friable vegetation, non-valvular cardiac manifestations) are pointing towards fungal IE. These reports, however, are not standardized and a publication bias towards rare microorganisms or towards a favorable outcome might exist. Complications might be underreported, and important data such as diagnostic delay are absent or difficult to retrieve. Pharmacologic treatment is not fully standardized. Knowledge of resistant strains in this respect is important. Statistical analysis for the effect of complications and treatment modalities on outcome shows that any result should be treated cautiously. The current series is by no means a valid substitute for a well-designed series of fungal endocarditis. However, the better outcome with Candida and patients treated with surgery confirm earlier results. An international multicentric standardized registry of cases with fungal endocarditis in order to improve the outcome of this disease is highly needed. The effect of diagnostic delay on outcome remains elusive and should be resolved.

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