A Rare Complication of Spine Surgery: Guillain–Barré Syndrome

Huang, Sheng‐Li; Qi, Huaguang; Liu, Jingjie; Huang, Yajuan; Li, Xiang

doi:10.1016/j.wneu.2015.04.045

Cited by 29 publications

(24 citation statements)

References 18 publications

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“…In orthopedic literature, there have been a few case reports of Guillain-Barré syndrome occurring after trauma, total hip arthroplasty, and spine surgery. Only one study reported the incidence of GBS after spine surgery, one per 2000 cases [ 9 ]. While there are case reports of GBS occurring after spine surgery, there are no reports of GBS after revision surgery.…”

Section: Discussionmentioning

confidence: 99%

Guillain-Barré Syndrome After Revision Lumbar Surgery: A Case Report

Rashid

Kurra

Lavelle

2017

Cureus

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Guillain-Barré syndrome (GBS) is a term that is used to describe a group of immune-mediated peripheral neuropathies, with the most common feature being rapid polyradiculoneuropathy. The exact etiology of this syndrome is unknown. In the field of orthopedics, GBS has been reported to occur after total hip arthroplasty, orthopedic trauma, and spine surgery. We report a unique case of GBS after elective revision lumbar spine surgery. A 62-year-old female presented with persistent low back pain and radiculopathy and elected to have revision lumbar spine surgery. Approximately 24 to 36 hours after hospital discharge, she returned to the hospital with weakness in her legs. After an electromyography (EMG), the patient was diagnosed with GBS and placed on intravenous immunoglobulin (IVIG). She developed respiratory failure, which required intubation and eventually converted to a tracheostomy and was finally decannulated. Over the course of 12 months, she improved to her pre-surgical baseline, gaining 5/5 strength in her upper and lower extremities and was able to ambulate independently without any aids. This was a case of GBS that occurred in a patient approximately two weeks after revision lumbar surgery. GBS is a poorly understood and rare complication of lumbar spine surgery that needs to be recognized quickly to be effectively treated.

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Section: Discussionmentioning

confidence: 99%

Guillain-Barré Syndrome After Revision Lumbar Surgery: A Case Report

Rashid

Kurra

Lavelle

2017

Cureus

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“…Post-traumatic GBS is a rapidly progressive and severe neurologic complication that occurs after trauma [ 15 , 18 , 19 ]. Thus, when there is unexplainable progressive muscle weakness after trauma, GBS should be taken into consideration and corresponding measures should be taken to relieve the condition.…”

Section: Discussionmentioning

confidence: 99%

“…Reports of GBS in trauma patients is limited to case reports and no systematic research has been found so far discussing its immunological treatment. Therefore, an empiric course of intravenous immunoglobulin or plasma exchange might be valuable as it has been shown to improve prognosis [ 5 , 18 , 19 ]. Moreover, we found that some cases showed some clinical improvement, while others did not, when treated with intravenous methylprednisolone [ 15 , 17 ].…”

Section: Discussionmentioning

confidence: 99%

Clinical and electrophysiological features of post-traumatic Guillain-Barré syndrome

Xiao

Ding

et al. 2017

BMC Neurol

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BackgroundPost-traumatic Guillain-Barré syndrome (GBS) is a rarely described potentially life-threatening cause of weakness. We sought to elucidate the clinical features and electrophysiological patterns of post-traumatic GBS as an aid to diagnosis.MethodsWe retrospectively studied six patients diagnosed with post-traumatic GBS between 2014 and 2016 at Tianjin Medical University General Hospital, China. Clinical features, serum analysis, lumbar puncture results, electrophysiological examinations, and prognosis were assessed.ResultsAll six patients had different degrees of muscular atrophy at nadir and in two, respiratory muscles were involved. Five also had damaged cranial nerves and four of these had serum antibodies against gangliosides. The most common electrophysiological findings were relatively normal distal latency, prominent reduction of compound muscle action potential amplitude, and absence of F-waves, which are consistent with an axonal form of GBS.ConclusionsIt is often overlooked that GBS can be triggered by non-infectious factors such as trauma and its short-term prognosis is poor. Therefore, it is important to analyze the clinical and electrophysiological features of GBS after trauma. Here we have shown that electrophysiological evaluations are helpful for diagnosing post-traumatic GBS. Early diagnosis may support appropriate treatment to help prevent morbidity and improve prognosis.

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“…In contrast to well-established infectious etiology, the concept of posttraumatic GBS preceded by no risk factors other than trauma has been recently introduced. There have already been several reports of posttraumatic GBS, following physical damage from traffic accidents, falling, or surgery 1 , 7 , 11 – 14 , 17 , 18) . However, in all previous cases, the time from trauma to symptom onset was more than several days.…”

Section: Discussionmentioning

confidence: 99%

Posttraumatic Guillain-Barré Syndrome Immediately Following a Traffic Accident

et al. 2017

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Guillain-Barré syndrome (GBS) is an inflammatory demyelinating polyneuropathy characterized by areflexic paralysis. Most cases of GBS are preceded by an infection, however, posttraumatic GBS has also recently been reported. We report a case of posttraumatic GBS immediately following a traffic accident. We think this case is of clinical significance for practitioners because of the rare cause of a sudden flaccid paralysis following trauma.

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A Rare Complication of Spine Surgery: Guillain–Barré Syndrome

Cited by 29 publications

References 18 publications

Guillain-Barré Syndrome After Revision Lumbar Surgery: A Case Report

Guillain-Barré Syndrome After Revision Lumbar Surgery: A Case Report

Clinical and electrophysiological features of post-traumatic Guillain-Barré syndrome

Posttraumatic Guillain-Barré Syndrome Immediately Following a Traffic Accident

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