A Rare Mediastinal Tumor: Thymolipoma

Döngel, İsa; İmamoğlu, Hakan; Şahin, Ali Feyzullah; Yıldırım, Salih; Bayram, Mehmet

doi:10.15197/sabad.1.11.23

Cited by 4 publications

(5 citation statements)

References 7 publications

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“…Thymolipoma is a rare benign tumor originating in the anterior mediastinum, and comprises 2-9% of all thymic neoplasms (1). Cytogenetic analyses have demonstrated that thymolipoma is a neoplasm of thymic fat (2).…”

Section: Medical Image Of the Month: Thymolipomamentioning

confidence: 99%

“…There is no sex or age predilection and affected patients range in age from 3-76 years. Most patients remain asymptomatic until the size of the lesion produced local mass effects, resulting in symptoms such as cough, dyspnea, hemoptysis, chest pain and hoarseness (1,3). Autoimmune diseases, including myasthenia gravis, systemic lupus erythematosus, hypogammaglobulinemia, Graves' disease, and erythroblastopenia, may coexist in 10% patients (1).…”

Section: Medical Image Of the Month: Thymolipomamentioning

confidence: 99%

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Medical image of the month: thymolipoma

Paliwal¹,

Jaiswal²,

Sharma³

2019

Southwest J Pulm Crit Care

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Section: Medical Image Of the Month: Thymolipomamentioning

confidence: 99%

Section: Medical Image Of the Month: Thymolipomamentioning

confidence: 99%

Medical image of the month: thymolipoma

Paliwal¹,

Jaiswal²,

Sharma³

2019

Southwest J Pulm Crit Care

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“…Most frequently located in anterior mediastinum, thymolipoma is diagnosed in patients with ages ranging from two to 67 years, without gender predilection [8,9]. Microscopy shows a tumor mass composed by mature adipose tissue, without atypia, associated with foci of benign thymic tissue, mainly composed of epithelial cells [4,[10][11][12][13].…”

Section:  Introductionmentioning

confidence: 99%

Untitled

2021

Rom J Morphol Embryol

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Thymolipoma is an uncommon benign thymus lesion, with a partially deciphered etiopathogeny, being most frequently diagnosed in young patients, regardless of gender. Incidentally diagnosed in asymptomatic patients, larger thymolipomas lead to symptoms related to neighboring mediastinal structures compression, with an intensity which is correlated with the mass size. Our review presents the main epidemiological, pathogenic, clinicopathological and morphological characteristics of this rare pathology. Sometimes, thymolipomas may be associated with paraneoplastic syndromes, which are alleviated by the mass complete surgical resection. Imagistics may orientate the diagnosis, which is certified by the microscopic examination of the resection specimens. Extensive thymectomy remains the current therapeutic option and new tools have been developed to increase the accuracy of the surgical procedure to avoid incidental lesions of the important elements of the anterior mediastinum. Although rare, thymolipomas should be considered in the differential diagnosis of mediastinal masses and of paraneoplastic syndromes.

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“…[ 1 2 ] The majority of these tumors are clinically quiescent; however, symptomatic patients may present with dyspnea, tachypnea, chest pain, upper respiratory tract infections, and rarely myasthenia gravis. [ 3 4 5 ] Diagnosis should be confirmed radiologically during the preoperative work-up, with pathognomonic features demonstrated on both computed tomography (CT) scan and magnetic resonance imaging (MRI) and with fine-needle aspiration biopsy (FNAB). [ 4 6 7 8 9 ] TLs are benign neoplasms for which complete surgical excision is curative.…”

Section: Introductionmentioning

confidence: 99%