A Rare Presentation of Extramedullary Hematopoiesis in Post-polycythemic Myelofibrosis

Değertekin, Ceyla Konca; Akyürek, Nalân; Yağcı, Münci

doi:10.1007/s12288-012-0218-z

Cited by 2 publications

(1 citation statement)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, we could not have access to seven papers written in Japanese that were cited in one record 19 . Therefore, our study included 43 papers, describing 47 patients 6,9,19–59 …”

Section: Resultsmentioning

confidence: 99%

Cutaneous involvement in Ph‐negative myeloproliferative neoplasms: from extramedullary hematopoiesis to myeloid metastasis with histiocytic differentiation. A systematic review of the literature

Bonometti

2023

Int J Dermatology

View full text Add to dashboard Cite

Myeloid neoplasms may metastasize to the skin, presenting a wide range of clinical‐pathological features that often lead to a reduction in patients' survival. The presentation varies depending on the category of myeloid neoplasm and its prognostic significance. The literature has specifically focused on the features of acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and chronic myelomonocytic leukemia (CMML). In this article, we aimed to uncover the peculiarities of clonal skin proliferations in the course of Ph‐negative myeloproliferative neoplasms (MPNs). We conducted a systematic review and statistical analysis of the literature data. MPN patients mainly exhibited cutaneous extramedullary hematopoiesis, while a minority displayed cutaneous histiocytic lesions. Furthermore, these patients showed lower survival rates compared to the median survival of MPN patients, especially when calculating survival from the appearance of cutaneous lesions. Our work highlights, for the first time, the prognostic relevance and histological heterogeneity of cutaneous lesions in MPN. Moreover, it emphasizes the importance of dermatological and histological examinations when cutaneous lesions are present.

show abstract

“…However, we could not have access to seven papers written in Japanese that were cited in one record 19 . Therefore, our study included 43 papers, describing 47 patients 6,9,19–59 …”

Section: Resultsmentioning

confidence: 99%

Cutaneous involvement in Ph‐negative myeloproliferative neoplasms: from extramedullary hematopoiesis to myeloid metastasis with histiocytic differentiation. A systematic review of the literature

Bonometti

2023

Int J Dermatology

View full text Add to dashboard Cite

show abstract

Extramedullary haematopoiesis presenting with cardiac tamponade in a patient with polycythaemia vera

Haroun¹,

Elkis

Chen

et al. 2017

BMJ Case Reports

View full text Add to dashboard Cite

A 71-year-old man with a history of polycythaemia vera, diagnosed 4 years ago, presented to the emergency room with shortness of breath. A bedside echocardiogram revealed a large pericardial effusion with features concerning for pericardial tamponade. A left anterior thoracotomy and a pericardial window were emergently performed in the operating room and relieved the patient's symptoms. Histology evaluation of the pericardial fragments and pericardial fluid revealed the presence of trilineage haematopoietic elements without any increase in the blasts. A bone marrow core biopsy revealed an increase in reticulin fibre and increase in the number of blasts of 5%-10%, whereas peripheral blood testing was positive for JAK2 V617F mutation. This case report reviews the literature for cases of extramedullary haematopoiesis associated with myeloproliferative neoplasms.

show abstract

A Rare Presentation of Extramedullary Hematopoiesis in Post-polycythemic Myelofibrosis

Cited by 2 publications

References 37 publications

Cutaneous involvement in Ph‐negative myeloproliferative neoplasms: from extramedullary hematopoiesis to myeloid metastasis with histiocytic differentiation. A systematic review of the literature

Cutaneous involvement in Ph‐negative myeloproliferative neoplasms: from extramedullary hematopoiesis to myeloid metastasis with histiocytic differentiation. A systematic review of the literature

Extramedullary haematopoiesis presenting with cardiac tamponade in a patient with polycythaemia vera

Contact Info

Product

Resources

About