CLINICOPATHOLOGICAL CORRELATIONand the patient was further managed in an intensive care unit (ICU) setting.Further examination in the ICU revealed coarse crackles in the right infrascapular and infra-axillary areas. Bilateral plantars were muted. No other objective focal neurological deficits were noted. Post-return of spontaneous circulation (ROSC ), he remained unresponsive and hypotensive, requiring dual ionotropic support to maintain a mean arterial pressure (MAP) of greater than 65 mm Hg. He was started on targeted temperature therapy for postresuscitation care. His electrocardiogram (ECG) showed sinus tachycardia. Rapid pointof-care evaluation revealed high anion gap metabolic acidosis (pH 6.739), normal blood glucose (97 mg/dL), and a normal
Case DesCriptionClinical Discussant: A 40-year-old otherwise healthy male, with a history of consuming a significant amount of alcohol in the past (100 gm/day for the last 10-12 years), on psychiatry follow-up and anticraving medication (naltrexone), presented to the Emergency Department (ED) with a history of sudden onset loss of consciousness, followed by three episodes of spontaneous generalized tonic-clonic seizures while standing for organized physical activity early in the morning. His peers had not noticed anything unusual before the incident. He had not complained of feeling unwell, chest pain, difficulty in breathing, or dizziness.The patient was started on oxygen at the nearest medical facility and transferred to our hospital. He did not regain consciousness on the way and had two more episodes of generalized tonic-clonic seizures in the ambulance. Each episode lasted for around 6-7 minutes and subsided spontaneously. On arrival at the ED, the patient was found to be in cardiac arrest. He was unresponsive and pulseless. His pupils were bilaterally equal but sluggishly responsive. His blood pressure was unrecordable. Code Blue was activated, and cardiopulmonary resuscitation (CPR) was initiated as per advanced cardiovascular life support (ACLS) protocol. He was given IV fluid boluses, and IV adrenaline and atropine. The defibrillator revealed a nonshockable rhythm [pulseless electrical activity (PEA)]; therefore, cardioversion was not attempted. Return of spontaneous circulation was achieved within 6 minutes. An advanced airway was secured,