A rare presentation of Pulmonary Lymphangitic Carcinomatosis in cancer of lip: case report

Abstract

Squamous cell carcinoma of lip is a common malignancy in Indian subcontinent. Metastatic spread is infrequent. Although advanced tumours spread to lymph nodes in the neck, it does not typically present with lung metastasis or with lymphangitic carcinomatosis. We describe a patient who developed cough and increasing dyspnoea while on treatment for carcinoma of lip. Chest x-ray and computed tomography were consistent with lymphangitic carcinomatosis. Lymphangitic carcinomatosis occurs with many different primary tumours and can rarely occur in oral cancers. This is the first report from carcinoma of lip.

Pulmonary Lymphangitic Carcinomatosis due to Metastatic Adenocarcinoma of the Lung: A Case Report

“…The history of cancer or surgery and characteristic features identified on lung CT scans can be used to diagnose PLC after exclusion of interstitial pneumonia, pulmonary fibrosis, sarcoidosis, pulmonary embolism, heart failure and hematogenous disseminated pulmonary tuberculosis. Biopsy and subsequent pathologic examination are not required for the diagnosis of PLC [7,8]. In the early stages, lung CT shows interstitial lesions, linear and reticular shadows and interlobar fissure thickening.…”

Pulmonary lymphangitic carcinomatosis in liver carcinoma: a rare case report and literature review

“…Most PLCs originate from adenocarcinomas, and they are most often due to lung cancer, followed by breast cancer and gastric cancer [ 2 , 3 ]. Patients with renal cancer, cervical cancer, thyroid cancer and melanoma rarely develop PLC [ 4 - 6 ]. The pathologic features of PLC include infiltration of cancer cells and interstitial edema in and around lymphatic vessels as well as infiltration of inflammatory cells caused by lymph node metastasis in the lung.…”

“…The history of cancer or surgery and characteristic features identified on lung CT scans can be used to diagnose PLC after exclusion of interstitial pneumonia, pulmonary fibrosis, sarcoidosis, pulmonary embolism, heart failure and hematogenous disseminated pulmonary tuberculosis. Biopsy and subsequent pathologic examination are not required for the diagnosis of PLC [ 6 , 9 ]. In the early stages, lung CT shows interstitial lesions, linear and reticular shadows and interlobar fissure thickening.…”

Lymphangitic Carcinomatosis of Unknown Primary: A Case Report

“…This patient presented with progressive dyspnea and dry cough, fever and weight loss. According to Babu et al 6 the most common cough and significant weight loss during last 6 months. The patient had also history of low grade intermittent fever along with night sweats.…”