A rare retroperitoneal schwannoma in a patient with neurofibromatosis Type 2

Patrinou, Alexandra; Malindretos, Pavlos; Koutroubas, Georgios; Anagnostou, Nikolaos; Argiraki, Elefteria; Syrganis, Christos

doi:10.1093/ndtplus/sfq039

Cited by 4 publications

(6 citation statements)

References 10 publications

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“…The malignant peripheral nerve sheath tumours (MPNST) is defined as any malignant tumour differentiating into or deriving from the peripheral nerve sheath cells, with nonspecific symptoms, having high risk of recurrence locally and distant metastasis. 5,8 MPNST is particularly rare, affecting general population with an incidence of 0.001% and extremely rarespindle cell sarcoma in children, accounting for approximately 5-10% of nonrhabdomyosarcoma soft tissue sarcomas. 8,9 Schwannoma are tumours that are arise from the Schwann cells of peripheral nerve fibre and are generally found in the head, neck and extremities.…”

Section: Discussionmentioning

confidence: 99%

“…All MPNST characteristically demonstrate intense and uniform staining for S-100 protein. 5 These are more aggressive and are likely to have a high incidence of local recurrence after excision. Chances of distant metastasis are also high.…”

Section: Discussionmentioning

confidence: 99%

“…Regarding prognosis, 10 and 20-year survival among patients having onset of symptoms at younger age (<25 years) is 80%, 60% and 28%, respectively. 5 In contrary, the rate of survival among patients with onset of symptoms more than 25 years of age is 100%, 87% and 62%, respectively. Better survival rates are reported in patients with smaller size of tumor at the time of diagnosis (<2 cm in diameter).…”

Section: Introductionmentioning

confidence: 96%

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Rare case of giant retroperitoneal sarcoma

et al. 2019

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Schwannomas are benign nerve sheath tumors. Malignant schwannomas have been reported in literature but they frequently originate from the conversion of plexiform neurofibromatosis rather from the malignant degeneration of a benign schwannoma. Large retroperitoneal schwannomas are extremely rare tumours. They usually reach a large size when they arise retroperitoneally, which might raise suspicion for malignancy. Such tumors predominate in women schwannomas are usually solitary, slow growing and non-aggressive neoplasm usually found in head and neck region. Retroperitoneal schwannomas are usually large size are rare and are difficult to diagnose clinically. Nevertheless, the mainstay of management remains surgical removal and alternatively, the radio-therapy may prove to be effective. This case report of a 55 yrs male is based on such a patient in whom the diagnosis was established with great difficulty and intraoperative findings were something we had never encountered before. On examination:A visible lump seen in right iliac and right lumbar fossa, divarication of rectii seen.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 96%

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Rare case of giant retroperitoneal sarcoma

et al. 2019

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“…Miyagi T reported a posterior pararenal schwannoma with a diameter of 3.0 x 2.5 cm in 1986 (4). In 2010, a patient suffering from Neurofibromatosis Type 2 found a schwannoma posterior and inferior to the left kidney, measuring 9.5 x 4 x 4 cm (5). In 2013, Liu et al mentioned eight patients with retroperitoneal schwannomas in the anterior pararenal space (6).…”

Section: Discussionmentioning

confidence: 99%

Giant posterior pararenal schwannoma: A�case report and review of literature

Peng

Zhou

et al. 2018

mol clin onc

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Schwannomas, arising from Schwann cells of peripheral nerve sheaths, are primarily benign tumors. They are rarely found in the retroperitoneal space. To date, ~30 cases on giant retroperitoneal schwannomas have been reported. Those with a location of pararenal space are even rarer. Clinically, they are often misdiagnosed as malignancies. In the present study, a case of a 35-year-old woman with a giant schwannoma measuring 13 × 8.5 × 6.5 cm in the posterior pararenal space of left retroperitoneum was presented, which was thought to be a malignant tumor from the result of computed tomography scan. Later postoperative pathology and immunohistochemistry were consistent with benign schwannoma. To the best of our knowledge, this was the largest posterior pararenal schwannoma reported in literature. It is significant to report this case, and summarize the characteristics, diagnosis, treatment and prognosis of the similar cases. Furthermore, a brief review of the previously published cases in literature is provided.

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“…2,5 Sua apresentação é mais comum entre 30-60 anos, sendo 60-66% dos casos no gênero feminino. 3,4,6 Dos schwannomas retroperitoneais, até 66% exibem componentes císticos.…”

Section: 24unclassified

Retroperitoneal cellular schwannoma

Queiroz¹,

Rocha²,

Félix³

et al. 2017

Medicina (Ribeirão Preto)

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RESUMO ABSTRACTWe present the case of a female patient, 35 years old, who had a complaint of sporadic left flank pain for 5 years. She said she had no comorbidities. The results of the laboratory tests did not show abnormalities. Previous ultrasonography of the urinary tract (without the use of color Doppler) described a possible single cyst postero-inferiorly to the left renal pelvis. In recent ultrasound we observed that topography massive oval formation markedly hypoechoic with discrete intermingled flow. Subsequent abdominal computed tomography and magnetic resonance imaging characterized retroperitoneal mass along the hilum of the left kidney, associated with renal dimensional reduction and ipsilateral hydronephrosis.Histological diagnosis after tumor excision: cell schwannoma (Antoni A histological standard only).

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A rare retroperitoneal schwannoma in a patient with neurofibromatosis Type 2

Cited by 4 publications

References 10 publications

Rare case of giant retroperitoneal sarcoma

Rare case of giant retroperitoneal sarcoma

Giant posterior pararenal schwannoma: A�case report and review of literature

Retroperitoneal cellular schwannoma

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