A Rare Trifocal Presentation of Clostridium septicum Myonecrosis

Wiersema, Brent; Scheid, D. Kevin; Psaradellis, Telly

doi:10.3928/01477447-20080301-43

Cited by 7 publications

(3 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Early-awareness in order to make a prompt diagnosis and urgent and thorough surgical debridement is essential to improve survival [22]. A multidisciplinary team approach by multiple departmental doctors such as general physicians, orthopedic surgeons, dermatologists, pathologists, co-medical staff such as nurses, pharmacists, and laboratory technicians is necessary to manage these patients because those infections require intensive care pre-and post-operatively [23].…”

Section: Discussionmentioning

confidence: 99%

Rapidly Progressive Fatal Gas Gangrene due to Clostridium Septicum in a Patient with Colon Cancer Revealed by Autopsy

Haruka¹,

Gomi²,

Fukushima³

et al. 2017

Int J Crit Care Emerg Med

View full text Add to dashboard Cite

Gas gangrene is a rare, life-threatening deep skin infection typically related to contaminated wounds, although it may occur without injury. Non-traumatic gas gangrene due to Clostridium spp. is most commonly caused by Clostridium septicum. We present the case of a patient who expired of atraumatic gas gangrene due to Clostridium septicum. C. septicum infection is rapidly progressive and is associated with colorectal cancer and diabetes mellitus. We emphasize that it is important to diagnose and treat patients with gas gangrene by early recognition and aggressive debridement.

show abstract

Section: Discussionmentioning

confidence: 99%

Rapidly Progressive Fatal Gas Gangrene due to Clostridium Septicum in a Patient with Colon Cancer Revealed by Autopsy

Haruka¹,

Gomi²,

Fukushima³

et al. 2017

Int J Crit Care Emerg Med

View full text Add to dashboard Cite

show abstract

“…Furthermore the classic bronze or reddish discoloration of skin due to clostridial infections may not be commonly visualized due to the already tanned skin complexion of Asians, although Case 2 demonstrated typical skin manifestations with bullae formation. In Case 1 the possible missed sign was the out of proportion pain with a sense of weakness and heaviness which are nonspecific presenting features of gas-forming NF [9]. These were mistaken for a milder form of infection, cellulitis, with absence of superficial skin manifestations.…”

Section: Discussionmentioning

confidence: 99%

Necrotizing fasciitis – a diagnostic dilemma: two case reports

et al. 2014

View full text Add to dashboard Cite

IntroductionNecrotizing soft tissue infections can affect various tissue planes. Although predisposing etiologies are many, they mostly center on impaired immunity occurring directly or indirectly and loss of integrity of protective barriers which predispose to infection. The nonspecific presentation may delay diagnosis and favor high mortality.Case presentationTwo case vignettes are presented. The first patient, a 44-year-old healthy South Asian man with a history of repeated minor traumatic injury presented to a primary health care center with a swollen left lower limb. He was treated with antibiotics with an initial diagnosis of cellulitis. Because he deteriorated rapidly and additionally developed intestinal obstruction, he was transferred to our hospital which is a tertiary health care center for further evaluation and management. Prompt clinical diagnosis of necrotizing soft tissue infection was made and confirmed on magnetic resonance imaging as necrotizing fasciitis. Urgent debridement was done, but the already spread infection resulted in rapid clinical deterioration with resultant mortality. The second patient was a 35-year-old South Asian woman with systemic lupus erythematous receiving immunosuppressive therapy who developed left lower limb pain and fever. Medical attention was sought late as she came to the hospital after 4 days. Her condition deteriorated rapidly as she developed septic shock and died within 2 days.ConclusionsNecrotizing fasciitis can be fatal when not recognized and without early intervention. Clinicians and surgeons alike should have a greater level of suspicion and appreciation for this uncommon yet lethal infection.

show abstract

“…Other possible strains are Clostridium haemolyticum , Clostridium oedematiens , Clostridium novyi , Clostridium histolyticum , or Clostridium septicum [2, 4]. In the even scarcer cases of nontraumatic gas gangrenes, Clostridium septicum is typically the culprit pathogen [5]. …”

Section: Introductionmentioning

confidence: 99%

Foudroyant Course of an ExtensiveClostridium septicumGas Gangrene in a Diabetic Patient with Occult Carcinoma of the Colon

Hartel

Kutup

Gehl

et al. 2013

Case Reports in Orthopedics

View full text Add to dashboard Cite

Background. Spontaneous gas gangrene is a rare disease in which Clostridium septicum frequently can be detected. After an incubation period of 5–48 hours, a very painful swelling is accompanied by a rapidly spreading toxic-infectious clinical picture ultimately leading to septic shock and multiple organ failure. We present a case of a completely documented rare infectious disease with triage findings including initial vital signs, initial medical findings, and the emergency lab., radiological, intraoperative, histopathological, microbiological, and postmortem results. After initial diagnosis of the underlying disease, the patient has been immediately transferred to the operating theatre. The laboratory findings reflect the devastating effect of toxin α which is a toxin typically produced by C. septicum. The patient presented both an anaemia and a manifest coagulopathy as well as an onset of multiple organ failure. Despite the aggressive medical and surgical measures that have been taken, this patient could not be saved. Discussion. The case presented vividly emphasises the difficulty to identify these cases early enough to save a patient. This documentation may help health care providers to identify this life threatening disease as early as possible in future cases.

show abstract

A Rare Trifocal Presentation of Clostridium septicum Myonecrosis

Cited by 7 publications

References 12 publications

Rapidly Progressive Fatal Gas Gangrene due to Clostridium Septicum in a Patient with Colon Cancer Revealed by Autopsy

Rapidly Progressive Fatal Gas Gangrene due to Clostridium Septicum in a Patient with Colon Cancer Revealed by Autopsy

Necrotizing fasciitis – a diagnostic dilemma: two case reports

Foudroyant Course of an ExtensiveClostridium septicumGas Gangrene in a Diabetic Patient with Occult Carcinoma of the Colon

Contact Info

Product

Resources

About