A Rare Tumor of the Diaphragm: Pleomorphic Rhabdomyosarcoma

Deniz, Pelin Pınar; Kalaç, Nilgün; Ucoluk, Gulnur Onde; Samurkaşoğlu, Belgin; Taştepe, Abdullah İrfan; Gülhan, Erkmen; Demırağ, Funda

doi:10.1016/j.athoracsur.2007.11.028

Cited by 10 publications

(7 citation statements)

References 7 publications

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“…There are four histologic classes of rhabdomyosarcoma: pleomorphic, alveolar, botryoid, and embryonal. 4 Embryonal is the most common type (58%). 45 It can occur at any site, but is usually found in the head and neck region (42%), urogenital tract Tumors of the Diaphragm (34%), or extremities (11%).…”

Section: Malignant Primary Tumors Of the Diaphragm Rhabdomyosarcomamentioning

confidence: 99%

Tumors of the Diaphragm

Kim

Hofstetter

2009

Thoracic Surgery Clinics

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Section: Malignant Primary Tumors Of the Diaphragm Rhabdomyosarcomamentioning

confidence: 99%

Tumors of the Diaphragm

Kim

Hofstetter

2009

Thoracic Surgery Clinics

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“…2 Some patients with PDT may be asymptomatic, while others can manifest cough, dyspnoea, dysphagia, anorexia, nausea and vomiting as a consequence of gastric compression. 3 PDTs are generally surgically removed if patients are symptomatic or if there is a doubt about the diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Primary diaphragmatic undifferentiated pleomorphic sarcoma in a cat

Bonazzi¹,

Morabito²,

Brunetti

et al. 2021

Journal of Feline Medicine and Surgery Open Reports

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Case summary A 5-year-old neutered female domestic shorthair cat was referred for acute onset of dyspnoea. Thoracic radiographs performed by the referring veterinarian revealed the presence of pleural effusion. Upon presentation, the cat was dyspnoeic, and cardiopulmonary auscultation revealed muffled heart sounds and bilaterally increased bronchovesicular sounds. Radiographic study of the thorax revealed bilateral pleural effusion and a soft tissue opacity in the dorsocaudal region of the left hemithorax. A whole-body contrast-enhanced CT scan identified a soft tissue mass arising from the left diaphragmatic crus. Transthoracic ultrasound-guided fine-needle aspiration (FNA) of the mass was performed and the result was consistent with a malignant mesenchymal neoplasia, showing giant cells. Cytoreductive surgery was performed and the histopathology diagnosis of undifferentiated pleomorphic sarcoma was made. Adjuvant chemotherapy was then offered. Ten days after surgery pleural effusion recurred. Thoracic echography revealed the presence of a diaphragmatic thickening in the area of surgical resection. FNA of the thickening was consistent with mesenchymal neoplasia. Even when chemotherapy and supportive treatment with pain relief was instituted, the clinical condition of the cat worsened within a few days and it was euthanased 1 month after surgery. Relevance and novel information Primary diaphragmatic tumours (PDTs) have been rarely reported in human and in veterinary medicine, where only three cases have been described in the dog. To our knowledge, this is the first report to describe a PDT, specifically an undifferentiated pleomorphic sarcoma, in a cat.

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“…Fibröz doku kaynaklıdır. Genelde PMDT'ü teşhis edildiğinde plevra ve akciğere infiltre olup metastazları mevcuttur (16). "Rabdomyosarkom Çalışma Gurubu" hastalığı, histopatolojik olarak 4 guruba ayırmışlardır; a-Lokalize hastalık + komplet rezeksiyon, b-Mikroskopik hastalık ve/veya komplet rezeke nodal hastalık, c-Makroskopik hastalık + inkomplet rezeksiyon, d-Uzak metastaz.…”

Section: Primer Malign Diyafram Tümörleri (Pmdt)unclassified

Tumors of the Diaphragm

Baysungur¹

2014

Toraks Cer Bult

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Diaphragm tumors are rarely encountered. The most common benign tumor is lipoma, while the most frequent malignant tumor is fibrosarcoma. These tumors are generally seen in the 5th decade of life, and tumor incidence in equal in both sexes. There are no clinical characteristic signs as the diaphragm is adjacent to many organs. This is why a radiologically spotted mass usually causes confusion as to which organ it is associated with. Because of the difficulty in diagnosis, minimally invasive procedures like video-assisted thoracoscopy (VATS) and laparoscopy can be used. Primary treatment option for all malignant and benign diaphragm tumors is surgery. Combination therapy is suggested in locally advanced tumors; however, the survival time is short. Key words: Diaphragm, tumor, surgery ÖzetDiyafram tümörleri çok nadir görülen tümörlerdir. En sık rastlanan selim tümörü lipom, malign tümörü ise fibrosarkomdur. Kadın/erkek görülme oranı eşit olup, 40-50 yaş aralığında daha sık rastlanır. Diyaframın bir çok organa komşu olmasına bağlı tümörlerinin karakteristik bir kliniği yoktur. Bu yüzden radyolojik tespit edilen kitlenin hangi organa ait olduğu da çoğunlukla karışır. Tanı koymak zor olduğundan, video yardımlı torakoskopi (VATS) ve laparoskopi gibi minimal invaziv yöntemlerden de faydalanılabilinir. Tüm malign, benign diyafram tümörlerinde primer tedavi cerrahidir. Lokal ileri evre tümörlerde kombine tedavi önerilse de sağkalım kısadır.

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A Rare Tumor of the Diaphragm: Pleomorphic Rhabdomyosarcoma

Cited by 10 publications

References 7 publications

Tumors of the Diaphragm

Tumors of the Diaphragm

Primary diaphragmatic undifferentiated pleomorphic sarcoma in a cat

Tumors of the Diaphragm

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