A rate turbidimetric immunoassay for theophylline using biotin-avidin system

Obesity is a risk factor for being diagnosed with asthma, but there is conflicting evidence on whether obesity is a risk factor for lung function abnormalities characteristic of asthma. We studied a cohort of 488 subjects, 47% of whom were obese. Obese and non-obese subjects with asthma had similar airflow limitation and bronchodilator responsiveness, but obese participants had increased sleep disturbance and gastroesophageal reflux disease, higher cytokine levels, and a trend towards increased exacerbations when treated with theophylline. Obese and non-obese asthmatics have similar lung function abnormalities, but comorbidities and altered responses to medications may significantly affect asthma control in obese people.

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Effect of Obesity on Clinical Presentation and Response to Treatment in Asthma

Dixon

et al. 2006

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Clinical Trial of Low-Dose Theophylline and Montelukast in Patients with Poorly Controlled Asthma

Irvin

Kaminsky

Anthonisen

et al. 2007

Am J Respir Crit Care Med

107

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A rate turbidimetric immunoassay for theophylline using biotin-avidin system

Cited by 2 publications

References 22 publications

Effect of Obesity on Clinical Presentation and Response to Treatment in Asthma

Effect of Obesity on Clinical Presentation and Response to Treatment in Asthma

Clinical Trial of Low-Dose Theophylline and Montelukast in Patients with Poorly Controlled Asthma

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