A rational strategy based on experimental designs to optimize parameters of a liquid chromatography-mass spectrometry analysis of complex matrices

Abstract

Supplementary information Figure S1 : Key parameters for ESI detection optimized with DoE (red boxed text) and before DoE (purple boxed text)

A novel 2D metal–organic framework probe: a highly sensitive and visual fluorescent sensor for Al3+, Cr3+ and Fe3+ ions

“…[10][11][12] To date, conventional detection methods including atomic absorption spectrometry (AAS), ion-coupled plasma-mass spectroscopy (ICP-MS), liquid chromatography with ultraviolet detection (LC-UV) and fluorescence detection have been applied to analyze metal ions. [13][14][15] Among them, fluorescence detection exhibits real-time detection, easy operation and high sensitivity. 16 Metal-organic frameworks (MOFs) are outstanding candidates for fluorescence sensors because of their adjustable structures, modified ligands and active sites, high surface areas and tunable physicochemical properties.…”

Next Challenges for the Comprehensive Molecular Characterization of Complex Organic Mixtures in the Field of Sustainable Energy

“…Liquid chromatography (LC) is also used as part of bio-oil characterization, with different columns such as C18 [72,75] and amide [76]. The one-dimensional LC analyses allowed identifying and quantifying some species but with a limited number.…”

Characterization of Heavy Products from Lignocellulosic Biomass Pyrolysis by Chromatography and Fourier Transform Mass Spectrometry: A Review

“…Mass spectra of a pyrolysis bio-oil obtained by LC–ESI (−) FTICR MS (top) and ESI (−) FTICR MS (bottom). Reprinted with permission from ref . Copyright 2019 Elsevier.…”

“…For example, phenolic compounds were predominant in the pyrolysis bio-oils of birch bark and kraft lignin, whereas levoglucosan and acetic acid were not detected in the previous bio-oils but in large amount in water rich fractions. The input of an LC separation step prior to FTMS for the extensive characterization of bio-oil was also shown by Reymond et al 150 The authors developed an online RPLC−UV/FTICR MS method, with ESI and APCI sources, in both positive and negative-ion modes. The achieved results were compared to those obtained by ESI (−) FTICR MS analysis.…”