A Real-Time Localization System for an Endoscopic Capsule Using Magnetic Sensors

Pham, Duc Minh; Aziz, Syed Mahfuzul

doi:10.3390/s141120910

Cited by 61 publications

(49 citation statements)

References 26 publications

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“…Finally, these studies describe the effectiveness of a simple and inexpensive endoscopic capsule, which is able to deliver powdered compounds to the duodenum of pigs, signifying the potential for use for studies aimed at delivering acidlabile compounds to the lower gastro-intestinal tract. Related studies have also signified the potential for tracking the location of the capsule within the GI tract (Pham and Aziz, 2014 …”

Section: Discussionmentioning

confidence: 99%

A simple and inexpensive enteric-coated capsule for delivery of acid-labile macromolecules to the small intestine

Miller

Parsons

Bresland

et al. 2015

J. Zhejiang Univ. Sci. B

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Understanding the ecology of the gastrointestinal tract and the impact of the contents on the host mucosa is emerging as an important area for defining both wellness and susceptibility to disease. Targeted delivery of drugs to treat specific small intestinal disorders such as small bowel bacterial overgrowth and targeting molecules to interrogate or to deliver vaccines to the remote regions of the small intestine has proven difficult. There is an unmet need for methodologies to release probes/drugs to remote regions of the gastrointestinal tract in furthering our understanding of gut health and pathogenesis. In order to address this concern, we need to know how the regional delivery of a surrogate labeled test compound is handled and in turn, if delivered locally as a liquid or powder, the dynamics of its subsequent handling and metabolism. In the studies we report on in this paper, we chose 13 C sodium acetate ( 13 C-acetate), which is a stable isotope probe that once absorbed in the small intestine can be readily measured non-invasively by collection and analysis of 13 CO 2 in the breath. This would provide information of gastric emptying rates and an indication of the site of release and absorptive capacity. In a series of in vitro and in vivo pig experiments, we assessed the enteric-protective properties of a commercially available polymer EUDRAGIT ® L100-55 on gelatin capsules and also on DRcaps ® . Test results demonstrated that DRcaps ® coated with EUDRAGIT ® L100-55 possessed enhanced enteric-protective properties, particularly in vivo. These studies add to the body of knowledge regarding gastric emptying in pigs and also begin the process of gathering specifications for the design of a simple and cost-effective enteric-coated capsule for delivery of acid-labile macromolecules to the small intestine.

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Section: Discussionmentioning

confidence: 99%

A simple and inexpensive enteric-coated capsule for delivery of acid-labile macromolecules to the small intestine

Miller

Parsons

Bresland

et al. 2015

J. Zhejiang Univ. Sci. B

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“…To make the spectrum allocation decisions, the parameters of the PU are estimated based on the sample sequence. Then, the CH makes a decision on the packet size and channel assignment based on the estimation results [33,34,35]. …”

Section: System Modelmentioning

confidence: 99%

Study of Multi-Armed Bandits for Energy Conservation in Cognitive Radio Sensor Networks

Zhang

Jiang

Huang

et al. 2015

Sensors

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Technological advances have led to the emergence of wireless sensor nodes in wireless networks. Sensor nodes are usually battery powered and hence have strict energy constraints. As a result, energy conservation is very important in the wireless sensor network protocol design and the limited power resources are the biggest challenge in wireless network channels. Link adaptation techniques improve the link quality by adjusting medium access control (MAC) parameters such as frame size, data rate, and sleep time, thereby improving energy efficiency. In this paper we present an adaptive packet size strategy for energy efficient wireless sensor networks. The main goal is to reduce power consumption and extend the whole network life. In order to achieve this goal, the paper introduces the concept of a bounded MAB to find the optimal packet size to transfer by formulating different packet sizes for different arms under the channel condition. At the same time, in achieve fast convergence, we consider the bandwidth evaluation according to ACK. The experiment shows that the packet size is adaptive when the channel quality changes and our algorithm can obtain the optimal packet size. We observe that the MAB packet size adaptation scheme achieves the best energy efficiency across the whole simulation duration in comparison with the fixed frame size scheme, the random packet size and the extended Kalman filter (EKF).

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“…In fact, the position estimation of the pill is currently very inaccurate by using proprietary software applications provided to hospitals [2], [3] so the doctor cannot precisely locate detected diseases. Besides, not only precise location but also an accurate tracking of the capsule is of fundamental importance for the future of this technology [4].…”

Section: Introductionmentioning

confidence: 99%

UWB RSS-Based Localization for Capsule Endoscopy Using a Multilayer Phantom and In Vivo Measurements

Barbi

Garcia-Pardo

Nevárez

et al. 2019

IEEE Trans. Antennas Propagat.

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In recent years, localization for capsule endoscopy applications using Ultra-Wideband (UWB) technology has become an attractive field of investigation due to its potential benefits for patients. Literature concerning performance analysis of RF-based localization techniques for in-body applications at UWB frequencies is very limited. Available studies mainly rely on Finite Difference Time Domain (FDTD) simulations, using digital human models and on experimental measurements by means of homogeneous phantoms. Nevertheless, no realistic analysis based on multilayer phantom measurements or through in vivo experiment has been reported yet. This paper investigates the performance of RSS-based approach for two-dimensional (2D) and three-dimensional localization (3D) in the UWB frequency band. For 2D localization, experimental laboratory measurements using a two-layer phantom based setup have been conducted. For 3D localization, data from a recently conducted in vivo experiment have been used. Localization accuracy using path loss (PL) models, under ideal and not ideal channel estimation assumptions, are compared. Results show that under not ideal channel assumption the relative localization error slightly increases for the 2D case but not for the in vivo 3D case. Impact of receivers selection on the localization accuracy has also been investigated for both, 2D and 3D, cases. Index Terms-Wireless capsule endoscopy (WCE), Ultra-Wideband (UWB), in-body localization, heterogeneous phantom, in vivo measurements.

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A Real-Time Localization System for an Endoscopic Capsule Using Magnetic Sensors

Cited by 61 publications

References 26 publications

A simple and inexpensive enteric-coated capsule for delivery of acid-labile macromolecules to the small intestine

A simple and inexpensive enteric-coated capsule for delivery of acid-labile macromolecules to the small intestine

Study of Multi-Armed Bandits for Energy Conservation in Cognitive Radio Sensor Networks

UWB RSS-Based Localization for Capsule Endoscopy Using a Multilayer Phantom and In Vivo Measurements

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