A real-time multiplex PCR assay for detection of the causative agents of rat bite fever, Streptobacillus moniliformis and zoonoticStreptobacillus species

Kelly, Aubree J.; Ivey, Melissa L.; Gulvik, Christopher A.; Humrighouse, Ben W.; McQuiston, John R.

doi:10.1016/j.diagmicrobio.2021.115335

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2024

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Cited by 6 publications

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“…2,4 Hence, other diagnostic tools such as PCR, gas-liquid chromatography and 16S-rRNA sequencing, should be considered to confirm these organisms. 1,9,10 16S rDNA sequencing is a newer technique used to identify unusual microorganisms that are challenging to culture.…”

Section: Discussionmentioning

confidence: 99%

Rat bite fever, a neglected and underdiagnosed entity: case report

Perez Mingan,

Pajaro,

Romero Rivera

et al. 2024

MOJCR

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Rat bite fever is a poorly recognised entity, characterised by a series of clinical manifestations in which fever and polyatrial involvement predominate. The unspecificity of the symptoms together with the difficulty in isolating the causative germ causes delays in diagnosis, so active questioning in search of previous contact with rats or rodents is the fundamental basis for early diagnosis and timely treatment of this entity. Delayed treatment can result in mortality in up to 10% of patients.

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