2014
DOI: 10.4236/ijcm.2014.58066
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A Real World Experience of Guidewire-Induced Perforations during Percutaneous Intervention and Their Successful Management

Abstract: Complication rates following percutaneous interventions have decreased over the past decade due to advancement in both interventional equipment and procedure technique. Despite these advances, the risk of iatrogenic perforations still exists with associated high morbidity and mortality. We are presenting three cases of guidewire-induced perforations including coronary artery and renal artery perforation with their complications and successful management in these case-series.

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Cited by 4 publications
(4 citation statements)
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“…Several risk factors have been identified for the perforation of vessels during these procedures, including all causes of increased stiffness of the medial artery (such as uncontrolled diabetes mellitus, hypertension, chronic kidney disease, and older age). 7 Abnormal anatomical features and tortuosity, more prominently in cases of using straight‐tipped wires and use of large sheaths (mainly for transcatheter aortic valve implantation and endovascular abdominal aortic repair) are risk factors that cause a higher risk of vascular perforation. 6 , 8 Another known risk factor for vessel perforation is using a catheter and leading it forward without wire.…”
Section: Discussionmentioning
confidence: 99%
“…Several risk factors have been identified for the perforation of vessels during these procedures, including all causes of increased stiffness of the medial artery (such as uncontrolled diabetes mellitus, hypertension, chronic kidney disease, and older age). 7 Abnormal anatomical features and tortuosity, more prominently in cases of using straight‐tipped wires and use of large sheaths (mainly for transcatheter aortic valve implantation and endovascular abdominal aortic repair) are risk factors that cause a higher risk of vascular perforation. 6 , 8 Another known risk factor for vessel perforation is using a catheter and leading it forward without wire.…”
Section: Discussionmentioning
confidence: 99%
“…Complication rates following percutaneous interventions have decreased over the past decade due to advancements in both interventional equipment and procedure technique [3]. Despite these advances, the risk of iatrogenic perforation still exists with associated high morbidity and mortality.…”
Section: Discussionmentioning
confidence: 99%
“…Conservative management strategy for perforation of small peripheral artery includes rapid reversal of anticoagulation or antiplatelet therapy, balloon tamponade, i.e. prolonged inflation of an angioplasty balloon proximal to or at the level of the perforation to seal the site of perforation, and if leakage persists, occlusion of the distal vessel by delivery of thrombin, collagen, polyvinyl alcohol, gelfoam, subcutaneous fat, or even autologous blood using a microcatheter at the target vessel site [5] as well as coronary artery perforation [1][2][3][4][5]. Further surgical management may be indicated if hemostasis is not achieved conservatively.…”
Section: Discussionmentioning
confidence: 99%
“…Risk factors for vessel perforation include all comorbidities that promote medial artery calcification, such as hypertension, diabetes, and chronic renal failure, which lead to increased arterial stiffness [ 4 ]. Vascular anatomic variants and tortuosity, especially when utilizing a straight tipped wire, can predispose to vascular perforation [ 5 ].…”
Section: Introductionmentioning
confidence: 99%