A reappraisal of the use of ergometrine

Dumoulin, J. G.

doi:10.3109/01443618109067375

Cited by 47 publications

(28 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Uterotonic drugs studied in the AMTSL include Oxytocin, Methylergometrine, Syntometrine, Prostaglandin analogues in varying doses and different routes of administration with different results [7]- [12].…”

Section: Introductionmentioning

confidence: 99%

Oxytocin versus Methylergometrine in the Active Management of Third Stage of Labour

Boopathi¹,

Nayak²,

Rao³

et al. 2014

OJOG

View full text Add to dashboard Cite

Objective: To compare the efficacy of Oxytocin versus Methylergometrine in active management of third stage of labour in reducing risk of postpartum hemorrhage. Methods: This study was carried out by randomly assigning into two groups with 150 women in each group. Group 1 included patients who received injection Oxytocin 10 IU intramuscular within one minute of the birth of the baby. Injection Methylergometrine (0.2 mg) was given intravenously at the delivery of anterior shoulder of the baby to women in Group 2. Outcome measures were the duration of third stage, blood loss, pre and post-delivery hematocrit, side effects and incidence of PPH. Statistical analysis was done using Chi square test, Fischers test, Mann Whitney test, and t test. p < 0.05 was considered significant. Results: Mean duration of third stage of labour, mean blood loss, post-delivery fall in hematocrit and need for additional uterotonics were significantly less in the Group 2. However side effects like nausea, vomiting and rise in blood pressure were significantly higher in women in Group 2 (p = 0.000). Conclusion: Methylergometrine is more effective than Oxytocin in reducing the duration of third stage of labour and blood loss but has significant side effects like nausea, vomiting and rise in blood pressure.

show abstract

Section: Introductionmentioning

confidence: 99%

Oxytocin versus Methylergometrine in the Active Management of Third Stage of Labour

Boopathi¹,

Nayak²,

Rao³

et al. 2014

OJOG

View full text Add to dashboard Cite

show abstract

“…Ergometrine is widely regarded as the best drug available for controlling blood loss from postpartum haemorrhage (Dumoulin, 1981). Despite routine third stage prophylaxis in the unit, there was obvious room for improvement in reducing blood loss at instrumental delivery.…”

Section: Discussionmentioning

confidence: 99%

A comparison of changes in maternal haemoglobin concentration following instrumental and normal delivery

Quinn

1993

Journal of Obstetrics and Gynaecology

View full text Add to dashboard Cite

The occurrence of primary postpartum haemorrhage and its relation to changes in maternal haemoglobin concentration following instrumental delivery were studied in 337 consecutive operative vaginal deliveries. The postpartum haemorrhage rate in the instrumental delivery group was 24.3 per cent compared with 4.4 per cent for a control group of spontaneous vertex deliveries. Following instrumental delivery 26 per cent had an excessive reduction in haemoglobin concentration. Estimated blood of blood loss at delivery correlated poorly with reduction in haemoglobin concentration, but in 7.4 per cent of the study group the postnatal haemoglobin concentration was less than 8 g/dl, compared with 0.9 per cent in the control group. Blood transfusions were given more frequently in the instrumental vaginal delivery group ( I 1.3 per cent) compared with the control group (1.4 per cent) and also when compared with women delivered by caesarean section (7 per cent). Improvement in securing haeniostasis promptly after instrumental delivery is needed if the incidence of excessive blood loss and subsequent blood transfusion is to be reduced. Downloaded by [University of Otago] at 17:08 18 July 2015 Quinn: Changes in maternal haemoglobin concentration following delivery 347 Gilbert L., Porter W. and Brown V. A. (1987) Postpartum haemorrhage-a continuing problem. British Journal of Obstetrics and Gynaecology 94, 67-7 1. Moir D. D. and Wallace G . (1967) Blood loss at forceps delivery. Journal of Obstetrics and Gynaecology of British Commonwealth 74, 424429. Prendiville W., Elbourne D. and Chalmers I. (1988) The effect of routine oxytocic administration in the management of the third stage of labour: an overview of the evidence from controlled trials. British Journal of Obsteirics and Gynaecology 95, 3-16. (1992) Neonatal and maternal morbidity in relation to the length of the second stage of labour.

show abstract

“…It has been proven that 40% of cases of postpartum hemorrhage can be prevented by active management of third stage of labor (4) . Several Uterotonic drugs like Oxytocin, Methylergometrine, Syntometrine, Prostaglandin analogues in varying doses and different routes of administration had been studied yielding different results (5)(6)(7)(8)(9) . This randomized study was conducted to compare Methylergometrine and Intraumbilical Oxytocin in terms of efficacy, duration of third stage, blood loss, adverse effects and reduction in incidence of postpartum hemorrhage and retained placenta.…”

Section: Introductionmentioning

confidence: 99%

A Comparative Study of the Efficacy of Intraumbilical Oxytocin and Intravenous Methyergometrine in the third Stage Bleeding

Balakrishnan¹

2018

jmscr

View full text Add to dashboard Cite

A reappraisal of the use of ergometrine

Cited by 47 publications

References 27 publications

Oxytocin versus Methylergometrine in the Active Management of Third Stage of Labour

Oxytocin versus Methylergometrine in the Active Management of Third Stage of Labour

A comparison of changes in maternal haemoglobin concentration following instrumental and normal delivery

A Comparative Study of the Efficacy of Intraumbilical Oxytocin and Intravenous Methyergometrine in the third Stage Bleeding

Contact Info

Product

Resources

About