A reassessment of diagnostic criteria and treatment of idiopathic urticarial vasculitis: a retrospective study of 47 patients

“…The most common laboratory indings in idiopathic UV are elevation of the erythrocyte sedimentation rate and reduction of serum complement levels [48]. UV is divided into two groups as mainly normocomplementemic UV (NUV) and hypocomplementemic UV (HUV), based on complement levels [51,54]. Systemic involvement is usually absent or minimal and the prognosis is beter in NUV patients.…”

Section: Urticarial Vasculitismentioning

confidence: 99%

“…However, there is a propensity to more severe multi-organ involvement in HUV patients [48]. The most common systemic manifestations are in the joints, kidneys, and lungs [52,54]. Gastrointestinal and neurologic involvement can also be seen [50,52].…”

Section: Urticarial Vasculitismentioning

confidence: 99%

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Urticarial Syndromes

Gökalp¹,

Bulur²

2017

A Comprehensive Review of Urticaria and Angioedema

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Urticaria is a common dermatological condition that can occur in acute and chronic forms. Common urticaria is generally easy to diagnose; however, urticarial syndromes should be considered in cases where lesions persist for greater than 24-36 h, the location of lesions has bilateral symmetry, urticarial lesions are accompanied by additional elementary lesions, and/or the patient presents with additional systemic symptoms. Additionally, urticarial syndromes should be considered for patients with typical urticarial lesions that do not respond to systemic antihistamine treatment. Hyperpigmentation or bruising can be observed following resolution of urticarial syndromes. Many cutaneous and systemic diseases can cause urticarial syndromes. Systemic causes of urticarial syndromes can afect multiple organ systems and may be accompanied by systemic symptoms such as fever, asthenia, and arthralgia. Clinicopathologic correlation is essential for the accurate diagnosis of urticarial syndromes. In this chapter, cutaneous and systemic etiologies of urticarial syndromes are reviewed.

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“…In a study of 312 patients, 47 histologically had urticarial vasculitis and of these 81% had extracutaneous symptoms [Tosoni et al 2009]. …”

Section: Aetiology and Work-upmentioning

confidence: 99%

Chronic spontaneous urticaria: latest developments in aetiology, diagnosis and therapy

Vestergaard

Deleuran

2015

Therapeutic Advances in Chronic Disease

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Diagnosis and classification of urticaria Urticaria is per definition the appearance of wheals and/or angioedema. However, as described in the following, there are many other diseases presenting with wheals and angioedema that are not chronic urticaria, e.g. allergic anaphylaxis. Wheals are characterized by three features: (1) swelling and erythema, (2) itching/burning sensation and (3) transient nature with the skin returning to normal within 1-24 hours. According to the European Academy of Allergy and Clinical immunology (EAACI), the Global Allergy and Asthma European Network (GA 2 LEN), the European Dermatology Forum (EDF) and the World Allergy Organization (WAO) guidelines [Zuberbier et al. 2014], which are the internationally accepted guidelines, urticaria can be classified according to duration and cause. Acute urticaria is defined as the occurrence of spontaneous wheals with or without angioedema for less than 6 weeks, whereas chronic urticaria is occurrence of hives with or without angioedema for 6 weeks or more. Chronic urticaria is classified according to whether it is inducible or not into chronic spontaneous urticaria or chronic inducible urticaria. Chronic spontaneous urticaria may be due to known (e.g. autoantibodies) or unknown causes. The inducible urticarias include cold urticaria, delayed pressure urticaria, solar urticaria, heat urticaria, vibratory urticaria, cholinergic urticaria, contact urticaria, and aquagenic urticaria. A patient may well have more than one type of urticaria. Most of the conditions mentioned are mainly mediated by histamine (Table 1). Wheals and angioedema are not always urticaria Type I allergies should be suspected from a thorough history that reveals consistent appearance of wheals or angioedema after ingestion/

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A reassessment of diagnostic criteria and treatment of idiopathic urticarial vasculitis: a retrospective study of 47 patients

Cited by 53 publications

References 11 publications

Ürtikeryal Vaskülit ve Hashimato Tiroiditi: Olgu Sunumu Eşliğinde Literatürün Gözden Geçirilmesi*

Ürtikeryal Vaskülit ve Hashimato Tiroiditi: Olgu Sunumu Eşliğinde Literatürün Gözden Geçirilmesi*

Urticarial Syndromes

Chronic spontaneous urticaria: latest developments in aetiology, diagnosis and therapy

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