A Recyclable Chiral Ru Catalyst for Enantioselective Olefin Metathesis. Efficient Catalytic Asymmetric Ring-Opening/Cross Metathesis in Air [J. Am. Chem. Soc. 2002, 124, 4954−4955].

Ruthenium‐Catalyzed Ring‐Closing Metathesis: Recent Advances, Limitations and Opportunities

“…Aryloxide complexes C50 and C51 are a recent addition to the family of highly active metathesis catalysts; C52, in comparison, exhibits modest activity, but opens the door to Ru-catalyzed asymmetric metathesis, as discussed below [108,139,149]. The activity of C50 and C51 is due in part to the low steric constraints within these complexes: steric demand is minimized by the planarity of the aryloxide and pyridine donors, in conjunction with an essentially twodimensional IMes ligand [150].…”

Racemization-free synthesis of atropisomeric 1-phenylpyrrole based diamines using diphenylphosphoryl azide

“…In the case of the widely used binaphthalene derived amino alcohol NOBIN, both methods (resolution and synthesis from optically active precursors) were published. 15,16 The synthetic method was used as the aromatic amine was prepared by Curtius reaction from enantiopure carboxylic acid and proved to be a highly stereoconvergent process. 16 Other axially chiral aromatic amines were also synthesized using this method preserving the optical activities.…”

Improved Chiral Olefin Metathesis Catalysts: Increasing the Thermal and Solution Stability via Modification of a C1‐Symmetrical N‐Heterocyclic Carbene Ligand

“…Both Mo-based and Ru-based catalysts have been studied and while Rubased catalysts have not reached the levels of efficacy provided by their Mo-based counterparts, the development of chiral Ru-based catalysts such as 1 and 2 has continued to gain momentum due to their stability to air and moisture and tolerance to functional groups ( Figure 1). [2][3][4] Recently, our group reported the synthesis of catalyst 4, bearing a C 1 -symmetrical N-heterocyclic carbene (NHC) unit, in which one of the N-substituents (typically large aryl groups) was replaced by a sterically unencumbered Me group. Further modification of the N-aryl group provided catalysts that were highly reactive and afforded good enantioselectivities in asymmetric desymmetrization reactions.…”