The aim of this paper is to advocate for the importance of meaningful leisure time for young people from a healthpromotion perspective using experiences from two youth centres in multicultural neighbourhoods in Sweden. Methods: In this practice-based study, data were collected between 2012 and 2014 at two youth centres in multicultural, socially deprived suburbs in Sweden using surveys with 12-to 16-year-old adolescents (n = 207), seven individual interviews with staff and three cooperation partners in the neighbourhoods, and six group interviews with adolescents (50% girls). Quantitative, qualitative and mixed methods were used for analysis. Results: As part of the youth centres' strategies, they are open and inclusive, foster supportive relationships, emphasise youth empowerment, and integrate family, school and community in their work. The youth centres are health-promoting settings with regard to four of the action areas in the Ottawa Charter: build healthy public policy, create supportive environments, strengthen community actions and develop personal skills. Conclusions: There is a need for a variety and a combination of various structured and unstructured leisure-time activities because young people's background and life situation plays a role for their participation in leisuretime activities. We conclude that youth centres are well placed to be or to become health-promoting settings if the activities takes place in a structured environment.