A Retrospective Analysis of Outcomes Using Three Common Methods for Immediate Breast Reconstruction

Abstract

High satisfaction rates were seen across all three reconstructive groups, with the highest satisfaction levels seen in the expander/implant group, despite higher reoperation rates and lower aesthetic scores for this group.

Fibrotic Changes after Postmastectomy Radiotherapy and Reconstructive Surgery in Breast Cancer

“…There are numerous reports assessing the interaction of breast reconstruction and local radiotherapy [4,11,13,21,22] in a variety of clinical settings. Comparison of the reported clinical outcomes is hampered by the complex matter of available surgical techniques of breast reconstruction, aspects of timing between radiotherapy and plastic surgery, inconsistent definition of endoints reported, and a small sample size in the majority of studies.…”

“…Fibrotic changes of the reconstructed breast induced by surgery and radiotherapy represent a frequent and consistently reported clinical challenge forming the basis for many secondary events ultimately summarized as "complication" in numerous reports [3,5,21]. We, therefore, focused our retrospective analysis on the incidence and time trends of fibrotic sequelae secondary to plastic surgery and radiotherapy.…”

Interaction of human adipose tissue-derived mesenchymal stromal cells with breast cancer cells

“…Abbreviations: bFGF -basic fibroblast growth factor, cMET -hepatocyte growth factor receptor, CXCR4 -SDF-1α (CXCL12) receptor, EGF-epidermal growth factor, EGFR -epidermal growth factor receptor, FBS -foetal bovine serum, GAPDH -glyceraldehyde 3-phosphate dehydrogenase, G-CSF -granulocyte-colony stimulating factor, GM-CSF-granulocyte monocyte-colony stimulating factor, HGF -hepatocyte growth factor, IFN-g -interferon γ, IL -interleukin, MCP-1 (CCL2) -monocyte chemoattractant protein-1, chemokine CCL2, MIP-1a (CCL3) -macrophage inflammatory protein-1alpha, MIP-1b (CCL4)-macrophage inflammatory protein-1beta, PDGF-BB -platelet-derived growth factor, RANTES (CCL5)-Regulated on Activation, Normal T-cell Expressed and Secreted, chemokine CCL5, SCF -stem cell factor, SDF-1α -stroma-derived factor 1α, chemokine CXCL12, TGF-β-transforming growth factor beta, TNF-a -tumor necrosis factor α, VEGF-vascular endothelial growth factor, VEGFR -vascular endothelial growth factor receptor For cosmetic purposes, some surgeons use this procedure for breast augmentation as a sole treatment or for correction of the capsular deformity [4][5]. However, position paper published by American Society of Plastic and Reconstructive Surgeons in 1987 predicted that fat grafting would compromise breast cancer detection [6].…”

Analysis of patient satisfaction and donor-site morbidity after different types of breast reconstruction

“…on the contrary, it is difficult to come by clear data regarding impact of various breast reconstruction alternatives on patient satisfaction and QoL. And these data are of grave importance to communicate to the patient in order to create realistic expectations regarding surgical outcomes (8)(9)(10)(11). Therefore, the objective of the study herein was to evaluate patient satisfaction and donor-site morbidity in a large sample population in five common types of breast reconstruction: expander/implant, latissimus dorsi myocutaneous (LD)-flap, LD-flap in combination with an implant, free transverse rectus abdominis musculocutaneous (TRAM)-flap, and deep inferior epigastric perforator (DIEP)-flap.…”