2013
DOI: 10.2106/jbjs.l.00844
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A Retrospective Analysis of Vertebral Body Fractures Following Epidural Steroid Injections

Abstract: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

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Cited by 46 publications
(25 citation statements)
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“…A large retrospective cohort study compared the data of 3,000 patients with spinal pain who received a lumbar ESI with the data of 3,000 matched controls who did not receive injections. Each ESI increased the fracture risk by 31% . It is therefore recommended to keep the corticosteroid exposure to a minimum, particularly for high‐risk patients such as the elderly and women with a prior history of osteoporosis or osteopenia …”
Section: Complications After Epidural Corticosteroids: Overviewmentioning
confidence: 99%
“…A large retrospective cohort study compared the data of 3,000 patients with spinal pain who received a lumbar ESI with the data of 3,000 matched controls who did not receive injections. Each ESI increased the fracture risk by 31% . It is therefore recommended to keep the corticosteroid exposure to a minimum, particularly for high‐risk patients such as the elderly and women with a prior history of osteoporosis or osteopenia …”
Section: Complications After Epidural Corticosteroids: Overviewmentioning
confidence: 99%
“…In some studies, the incidence rises with cumulative dose (146,147), but there may be an even stronger association between vertebral fracture incidence and mean daily dose (148,149). Local epidural glucocorticoid injections for spinal central or foraminal stenosis may also increase bone loss (150), and the risk of incident clinical vertebral fractures (151).…”
Section: Individual Clinical Characteristics Associated With Incidentmentioning
confidence: 99%
“…particulate preparations) can inhibit recovery of the hypothalamic-pituitary axis and can lead to decreased bone mineral density (101)(102)(103). Cushingoid symptoms, although rare, can persist for several months after steroid injections have been terminated (28,104).…”
Section: How I Do It: Spinal Injections For Pain Management Palmermentioning
confidence: 99%