A retrospective audit to evaluate the appropriateness and rationalization of Fresh Frozen Plasma usage in a tertiary care hospital

Kumar, Santosh; Kushwaha, Neerja; Tomar, Akshaya; Philip, Joseph; Biswas, Amit Kumar

doi:10.1016/j.mjafi.2021.04.016

Medical Journal Armed Forces India

2022

DOI: 10.1016/j.mjafi.2021.04.016

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A retrospective audit to evaluate the appropriateness and rationalization of Fresh Frozen Plasma usage in a tertiary care hospital

Santosh Kumar¹,

Neerja Kushwaha

Akshaya Tomar

et al.

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2024

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Cited by 1 publication

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“Assessment of the utilization of fresh frozen plasma in a training and research hospital: What does the high level of inappropriate use tell us?” A descriptive-analytical study with cross-sectional method.

Yazici,

Yilmaz,

Gokcebay

et al. 2024

Preprint

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Objective: Fresh frozen plasma (FFP) is a life-saving treatment agent when used correctly, but it is also the one which is the most inappropriately used among the blood components. The aim of this study is to evaluate FFP transfusion indications based on different clinics. Methods: The study was carried out with the data obtained as a result of retrospective reviewing of the data of a total of 500 patients from 10 different clinics. FFP Transfusion Evaluation Form was created after scanning national/international articles, guidelines, and similar publications regarding the use of FFP. Results: It was determined that FFP was used at a rate of 26.6 % within appropriate indications. In terms of mortality development, there was no difference between the indication groups (p=0,31). There was no difference between the indication groups in the number of cases in which INR decreased with FFP transfusion (p=0,14). While the mean aPTT levels decreased from 48,2±32,1 to 31±15,4 (p<0,01) after transfusion, the mean INR values decreased from 3,6±3,8 to 1,6±0,8 (p< 0,04). Conclusion: The high rate of inappropriate use of FFP both threatens patient health due to transfusion reactions and affects stock management in blood centers adversely. The results obtained from the study reveal that standards and guidelines should be established for the appropriate use of FFP, both on a hospital and hospital basis, and the process should be audited at regular intervals in terms of ensuring clinicians' compliance with them and appropriate use.

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“Assessment of the utilization of fresh frozen plasma in a training and research hospital: What does the high level of inappropriate use tell us?” A descriptive-analytical study with cross-sectional method.

Yazici,

Yilmaz,

Gokcebay

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

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A retrospective audit to evaluate the appropriateness and rationalization of Fresh Frozen Plasma usage in a tertiary care hospital

Cited by 1 publication

References 19 publications

“Assessment of the utilization of fresh frozen plasma in a training and research hospital: What does the high level of inappropriate use tell us?” A descriptive-analytical study with cross-sectional method.

“Assessment of the utilization of fresh frozen plasma in a training and research hospital: What does the high level of inappropriate use tell us?” A descriptive-analytical study with cross-sectional method.

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