A Retrospective Comparative Study of Outcomes in Patients of Perforated Peptic Ulcer Applied With Cellan-Jones Repair Versus Graham's Patch

Abstract

Perforated Peptic ulcer is a complication of peptic ulcer disease (PUD) and is a surgical emergency with high morbidity and mortality. This study was undertaken to compare the outcome in patients treated with Cellan-Jones repair and Grahams patch for the perforation of peptic ulcer (PPU). It is a retrospective study done on 50 patients operated for perforated peptic ulcer in the District Hospital at Al Ameen Medical College Hospital Bijapur Karnataka from 2002 to 2005. Patients with acute and chronic peptic ulcer perforation selected for surgery, out of 50 patients 38 patients selected for Cellan-Jones repair and 12 patients selected for Graham's patch. Statistical analysis using Chi-square test was used to study the outcome in patients treated with two different surgical procedures for that particular age, sex, and occupation. Age related morbidity and mortality was also compared in the given study. A total of 50 patients with perforated peptic ulcer 38 patient treated with Cellan-Jones repair and 12 patients applied with Graham's patch. The overall mortality rate is 6% with p-value ˂0/05; 95% C.I. This study shows that the patients treated with Cellan-Jones repair and Graham's patch for the perforated peptic ulcer is having almost same result. This indicates that both the surgical methods have better survival outcome.