A Retrospective Evaluation of Radiographic Outcomes in Immature Teeth With Necrotic Root Canal Systems Treated With Regenerative Endodontic Procedures

Bose, Raison S; Nummikoski, Pirkka V.; Hargreaves, Kenneth M.

doi:10.1016/j.joen.2009.06.021

Cited by 449 publications

(424 citation statements)

References 20 publications

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“…Quantitative methods using 2D data were successfully reported and validated (12,35). However, working with 2D data has its limitations such as image standardization and the lack of volumetric measurements.…”

Section: Clinical Researchmentioning

confidence: 99%

“…The most frequent pretreatment diagnosis of these cases was of pulpal necrosis with or without apical periodontitis. Postoperative recalls showed regression of clinical symptoms in addition to radiographic evidence of hard tissue formation and apical closure (6)(7)(8)(9)(10)12). However, the application of nonstandardized 2-dimensional (2D) radiographs to evaluate an increase in root length and dentin thickness should be interpreted with caution because a slight change in the angulation at the preoperative or recall appointment might produce inconsistent images and inaccurate interpretations (12).…”

Section: Introductionmentioning

confidence: 99%

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3-dimensional Analysis of Regenerative Endodontic Treatment Outcome

EzEldeen

Gorp

Dessel

et al. 2015

Journal of Endodontics

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Introduction: A growing body of evidence supports the regeneration potential of dental tissues after regenerative endodontic treatment (RET). Nevertheless, a standard method for the evaluation of RET outcome is lacking. The aim of this study was to develop a standardized quantitative method for RET outcome analysis based on cone-beam computed tomographic (CBCT) volumetric measurements. Methods: Five human teeth embedded in mandibular bone samples were scanned using both an Accuitomo 170 CBCT machine (Morita, Kyoto, Japan) and a SkyScan 1174 micro-computed tomographic (mCT) system (SkyScan, Antwerp, Belgium). For subsequent clinical application, clinical data and low-dose CBCT scans (preoperatively and follow-up) from 5 immature permanent teeth treated with RET were retrieved. In vitro and clinical 3-dimensional image data sets were imported into a dedicated software tool. Two segmentation steps were applied to extract the teeth of interest from the surrounding tissue (livewire) and to separate tooth hard tissue and root canal space (level set methods). In vitro and clinical volumetric measurements were assessed separately for differences using Wilcoxon matched pairs test. Pearson correlation analysis and Bland-Altman plots were used to evaluate the relation and agreement between the segmented CBCT and mCT volumes. Results: The results showed no statistical differences and strong agreement between CBCT and mCT volumetric measurements. Volumetric comparison of the root hard tissue showed significant hard tissue formation. (The mean volume of newly formed hard tissue was 27.9 [AE10.5] mm 3 [P < .05]). Conclusions: Analysis of 3-dimensional data for teeth treated with RET offers valuable insights into the treatment outcome and patterns of hard tissue formation. (J Endod 2015;-:1-8)

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Section: Clinical Researchmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

3-dimensional Analysis of Regenerative Endodontic Treatment Outcome

EzEldeen

Gorp

Dessel

et al. 2015

Journal of Endodontics

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“…A complete formation of the root apices was achieved with complete periapical healing. Ca(OH) 2 was applied as temporary filling material also in the apical regions, producing better results than placed beyond the coronal half [40]. In the first case, an apical plug of MTA was used for short-time apexification in a combined treatment method.…”

Section: Discussionmentioning

confidence: 99%

The Management of Crown Fracture of Immature Teeth by MTA and Calcium Hydroxide: Case Reports

Alhaddad¹,

Tarján²,

Rózsa³

2015

Dentistry

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“…They have suggested that calcium hydroxide can kill any type of remaining pulpar cells, including stem or progenitor cells that are presented in the tissue of the dental pulp or possibly alter the apex and its resident stem cells, which is critical for the continued development of the root. Also, Bose et al 20 mentioned that calcium hydroxide is effective for extending radicular length, only if it is placed short of working length of the root, and suggested that the material is not near the apical tissue, where the progenitor cells are located and can interfere with the revascularization process.…”

Section: Comparison Of the Degree Of Coronal Pigmentation In Extractementioning

confidence: 99%

Comparison of the degree of coronal pigmentation in extracted premolars after the application of bi-antibiotic and tri-antibiotic pastes

Mejía

Monterrsa

2015

Joralres

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Abstract:Objective: To compare the degree of pigmentation in coronal extracted premolars after applying bi-antibiotic and tri-antibiotic pastes. Method: Intentional non-probability sampling. A total of 30 healthy premolars which were extracted for orthodontic reasons and met the inclusion criteria were divided into 2 experimental groups and a control group of 10 teeth each. Group I (G1) was treated with bi-antibiotic paste, group II (G2) with tri-antibiotic paste; and group III or control (G3) was treated with saline solution. Two observers previously calibrated took the initial color sample from each tooth by giving them a value corresponding to the shade guide. After access opening and instrumentation, all teeth received the appropriate medication and color records were taken under the same initial light conditions for 30 days after the procedure. The obtained data were compiled into Excel for further descriptive and inferential analysis with SPSS 19.0. ANOVA test was used with a confidence level of 95%. Results: The degree of pigmentation was 1±0.9 in G1, 12.2±1.2 in G2 and 0.9±0.8 in G3. No statistically significant differences were found between G1 and G3 (p=0.8086), but there was between G1 and G2 (p<0.001), and G2 and G3 (p<0.001). Conclusion: The degree of pigmentation with tri-antibiotic paste was higher than the degree of pigmentation with bi-antibiotic paste used as temporary medication. No difference was found between the degree of pigmentation in the group treated with bi-antibiotic and the control group treated with saline solution. Bi-antibiotic paste did not show pigmentation in the crown of the extracted premolars.

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A Retrospective Evaluation of Radiographic Outcomes in Immature Teeth With Necrotic Root Canal Systems Treated With Regenerative Endodontic Procedures

Cited by 449 publications

References 20 publications

3-dimensional Analysis of Regenerative Endodontic Treatment Outcome

3-dimensional Analysis of Regenerative Endodontic Treatment Outcome

The Management of Crown Fracture of Immature Teeth by MTA and Calcium Hydroxide: Case Reports

Comparison of the degree of coronal pigmentation in extracted premolars after the application of bi-antibiotic and tri-antibiotic pastes

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