A retrospective HEART risk score comparation of acute non-traumatic chest pain patients in an emergency department in Spain

Arispe, Iris Nathalie San Román; Mora, Josep; Torres, Oriol Yuguero; Bravo, Marta Ortega

doi:10.1038/s41598-021-02682-5

Cited by 4 publications

(5 citation statements)

References 21 publications

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“…Nghiên cứu của chúng tôi cho thấy bệnh nhân nữ giới chiếm phần lớn 67,10%. Các nghiên cứu khác cho thấy bệnh nhân nam giới chiếm phần lớn, Tỉ lệ bệnh nhân nam giới theo nghiên cứu của Trần Nam Chung 66,70%, Melki 54%, Six 58,90%, Iris Nathalie San Román Arispe 57,70% [9,11,12,13]. Mặc dù nguy cơ mắc bệnh mạch vành ở nữ chậm hơn so với nam giới do có estrogen là yếu tố bảo vệ.…”

Section: Bàn Luậnunclassified

“…Nghiên cứu của Six cho thấy bệnh nhân có kết cục xấu có tỉ lệ bệnh sử nghi ngờ, ECG thay đổi, tuổi lớn, nhiều yếu tố nguy cơ, troponin tăng cao hơn (p < 0,05) [9]. Nghiên cứu của Iris Nathalie San Román Arispe cho kết quả tương tự [13]. Điểm HEART ở nhóm kết cục xấu cũng cao hơn so với kết cục tốt (6,70 và 3,68; p < 0,001).…”

Section: Bàn Luậnunclassified

“…Nghiên cứu của Melki, nhóm HEART 0 -3, tỉ lệ kết cục xấu 0,40% (1 bệnh nhân) [12]. Nghiên cứu của Iris Nathalie San Román Arispe, nhóm HEART 0 -3, tỉ lệ 2,50% (3 bệnh nhân) [13]. Nghiên cứu của Hossein Alimohammadi, tỉ lệ nhóm HEART 0-3 6,80% [15].…”

Section: Bàn Luậnunclassified

“…Nghiên cứu của Iris Nathalie San Román Arispe cho thấy AUC 0,80, CI 95% 0,74 -0,87, p < 0,001. Nghiên cứu của Trần Nam Chung, với điểm cắt > 4, thang điểm HEART có giá trị tiên lượng biến cố ở nhóm nghiên cứu với độ nhạy 84,20%, độ đặc hiệu 68,30%, diện tích dưới đường cong ROC là 0,831 (0,712 -0,915) [11,13,15].…”

Section: Bàn Luậnunclassified

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Study on application of the HEART score in stratifying risk among patients with chest pain in the Emergency and Stroke Center of Hue University of Medicine and Pharmacy Hospital

Nguyen Khanh

2023

JMP

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Background: Chest pain is one of the most common reasons to attend the emergency department, accounting for approximately 10% of non-injury-related visits. Coronary artery disease is an important cause of chest pain that should be evaluated and managed early. The HEART score is designed to stratify the risk of emergency patients with undifferentiated chest pain, to identify high-risk patients who require more resources or need early emergency treatment, and low-risk patients to avoid unnecessary hospitalization. In my country, there have not been many studies on the HEART score yet. Objective: To evaluate the value of the HEART sore in risk stratification among patients with chest pain in the emergency department. Methods: Data used from 70 patients presented with chest pain to Emergency-Stroke Center of Hue university hospital. The HEART score was calculated. Outcome was occurrence of MACE (mortality, AMI, PCI, CABG) within 30-days of initial presentation. Results: Patient demographics include an average age of 63.80, 67.10% female, and 41.40% with history of hypertension, 21.40% with history PCI. 14.30% of patients met the outcome. The percent of patients with 30-day MACE with HEART score between 0 and 3, 4 - 6, and 7 - 10 was 4.30%, 10.50%, and 55.60%, respectively. With the cut-off of ≥ 4 points, the HEART score had prognostic value for the events in the study group with a sensitivity of 90%, a specificity of 63.3%, the area under the ROC curve was 0.86 (95% CI 0.71 - 1.00). Conclusion: The HEART score was valuable in risk stratification patients with chest pain in emergency department. Key words: HEART score, chest pain, emergency department.

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Study on application of the HEART score in stratifying risk among patients with chest pain in the Emergency and Stroke Center of Hue University of Medicine and Pharmacy Hospital

Nguyen Khanh

2023

JMP

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“…It has been reported that the incidence of major adverse cardiovascular events (MACEs) in patients with acute chest pain is higher than that in the normal population. Therefore, timely identification of the risk of chest pain and assessment of the patient's prognosis are conducive to guiding clinical treatment and improving the survival rate and are of great value for improving the prognosis [ 5 ]. In addition, due to the lack of accurate symptom manifestations of acute chest pain and the mostly atypical ECG, the optimal treatment time is easily missed, and sudden cardiac events are possible [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Predictive Value of the HEART Score Combined with Hypersensitive C-Reactive Protein for 30 d Adverse Cardiovascular Events in Patients with Acute Chest Pain

Lin

Zhang

Tang

et al. 2022

Emergency Medicine International

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Purpose. This study aimed to explore the predictive value of the HEART score combined with hypersensitive C-reactive protein (hs-CRP) for 30 d major adverse cardiovascular events (MACEs) in patients with acute chest pain. Methods. 103 patients with acute chest pain admitted to the emergency department of our hospital from May 2020 to May 2022 were selected as the study subjects. The patients’ HEART score and plasma hs-CRP level were recorded. The patients were followed up for 30 d to observe whether MACE occurred. Results. Among 103 patients with acute chest pain, MACE occurred in 8 cases within 30 d of follow-up, and the probability of MACE was 7.76%. There was a statistically significant difference in 30 d MACE risk among patients with different HEART score stratification ( P < 0.05 ). The age, HEART score, and hs-CRP levels of patients in the MACE group were higher than those in the non-MACE group ( P < 0.05 ). The HEART score and the hs-CRP level were independent risk factors for 30 d MACE in patients with acute chest pain ( P < 0.05 ). The AUC of the HEART score combined with hs-CRP in the occurrence of 30 d MACE in patients with acute chest pain was 0.901, which was significantly higher than 0.720 and 0.758 of single detection. Conclusion. The HEART score combined with hs-CRP can better predict the occurrence of 30 d MACE in patients with acute chest pain.

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Comparison of heart, grace and TIMI scores to predict major adverse cardiac events from chest pain in a Spanish health care region

Arispe,

Sol,

Gil

et al. 2023

Sci Rep

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Acute non-traumatic chest pain (ANTCP) is the second cause of consultation in the Emergency department (ED). About 70% of all Acute Myocardial Infarctions present as non persistent ST-elevation acute coronary syndrome (NSTE-ACS) in the electrocardiogram. Our aim was to compare whether the HEART risk score is more effective than the GRACE and TIMI scores for the diagnosis and prognosis of Major Adverse Cardiac Events (MACE) at six weeks in patients with ANTCP and NSTE-ACS. A prospective cohort study was conducted with patients with ANTCP that attended an ED and a Primary Care Emergency Center (PCEC) from April 2018 to December 2020. The primary outcome was MACE at six weeks. Diagnostic performance was calculated for each scale as the Area under the Receiver Operating Characteristic (ROC) curve (AUC), sensitivity (SE), specificity (SP), and predictive values (PV). Qualitative variables were compared using the Chi-square test, and continuous variables were compared using the nonparametric Kruskal–Wallis test. We adjusted a logistic regression for risk groups, age, and gender to determine the effect of the HEART, GRACE, and TIMI scores on MACE. The degree of agreement (kappa index) was calculated in the categorical classification of patients according to the three risk scales. Cox proportional hazards regressions were performed for each scale and were compared using partial likelihood ratio tests for non-nested models. From a sample of 317 patients with ANTCP, 14.82% had MACE at six weeks. The AUC was 0.743 (95% CI 0.67–0.81) for the HEART score, 0.717 (95% CI 0.64–0.79) for the TIMI score, and 0.649 (95% CI 0.561–0.738) for the GRACE score. The HEART scale identified low-risk patients with a higher SE and negative PV than the GRACE and TIMI scores. The HEART scale was better than the GRACE and TIMI scores at diagnosing and predicting MACE at six weeks in patients with ANTCP and probable NSTE-ACS. It was also a reliable tool for risk stratification in low-risk patients. Its application is feasible in EDs and PCECs, avoiding the need for complementary tests and their associated costs without compromising patient health.

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A retrospective HEART risk score comparation of acute non-traumatic chest pain patients in an emergency department in Spain

Cited by 4 publications

References 21 publications

Study on application of the HEART score in stratifying risk among patients with chest pain in the Emergency and Stroke Center of Hue University of Medicine and Pharmacy Hospital

Study on application of the HEART score in stratifying risk among patients with chest pain in the Emergency and Stroke Center of Hue University of Medicine and Pharmacy Hospital

Predictive Value of the HEART Score Combined with Hypersensitive C-Reactive Protein for 30 d Adverse Cardiovascular Events in Patients with Acute Chest Pain

Comparison of heart, grace and TIMI scores to predict major adverse cardiac events from chest pain in a Spanish health care region

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