2021
DOI: 10.1016/j.jclinane.2020.110106
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A retrospective observational pilot study on the effects of dexmedetomidine on neurological outcomes after aneurysmal subarachnoid hemorrhage

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Cited by 2 publications
(2 citation statements)
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“…A recent correspondence from Esfahani et al, [ 49 ] investigating SAH patients who received dexmedetomidine for ICU sedation did not find an association with vasospasm protection or favorable clinical outcomes at discharge as measured by mRS and Glasgow Outcome scale. As noted by the authors, the study was limited by small sample size, non-standardized dexmedetomidine dosing and difference in the clinical severity between the compared groups.…”
Section: Anesthetics/adjuvants In DCI After Sahmentioning
confidence: 99%
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“…A recent correspondence from Esfahani et al, [ 49 ] investigating SAH patients who received dexmedetomidine for ICU sedation did not find an association with vasospasm protection or favorable clinical outcomes at discharge as measured by mRS and Glasgow Outcome scale. As noted by the authors, the study was limited by small sample size, non-standardized dexmedetomidine dosing and difference in the clinical severity between the compared groups.…”
Section: Anesthetics/adjuvants In DCI After Sahmentioning
confidence: 99%
“…Several experimental studies show dexmedetomidine provides significant protection against both EBI and DCI following SAH [ 21 , 22 , 47 , 48 ]. A clinical study supports the use of dexmedetomidine in SAH patients as it shows a favorable neurologic outcome [ 50 ] and another study finds no impact on the outcomes [ 49 ]. Benzodiazepines, specifically midazolam has been shown to associate with poor outcomes in SAH patients [ 40 , 51 ].…”
Section: Summary Of Anesthetics/adjuvants and Neurovascular Protection In Sahmentioning
confidence: 99%