A retrospective study of 1064‐nm Q‐switched Nd:YAG laser therapy for acquired bilateral nevus of Ota‐like macules

Abstract

Background The therapeutic efficacy of laser treatments for acquired bilateral nevus of Ota‐like macules (ABNOM) varies among studies, and few studies have evaluated the factors affecting therapeutic effects. Aims To evaluate the efficacy and safety of 1064‐nm Q‐switched Nd:YAG laser (QSNYL) therapy for ABNOM and to identify the factors influencing the outcome. Methods A total of 110 patients with ABNOM were retrospectively evaluated and received two‐to‐nine treatment sessions. The effects of different factors on the therapeutic effect were analyzed on the basis of the number of treatments, age at first treatment, skin type, lesion color, affected area, number of lesion sites, and presence of concomitant melasma. Results The curative effect was positively correlated with the treatment time and negatively correlated with the increasing age at first treatment (p < 0.05). The curative effect was better in patients with skin type III than those with type IV ( p < 0.05) and in patients with a lesion area of less than 10 cm2 than those with a larger affected area (p < 0.05). Additionally, the treatment effect was poorer in patients with concomitant melasma (p < 0.05). The treatment effect was not significantly correlated with the lesion color or number of affected sites (p > 0.05). Eleven patients (10%) developed postinflammatory hyperpigmentation (PIH). Conclusions Early and repeated QSNYL therapy achieved satisfactory results for ABNOM. The risk of PIH after laser treatment is highest among patients with older age, darker lesion color, and darker skin color. For patients with ABNOM with concurrent melasma, low‐energy laser therapy is recommended to reduce the risk of melasma aggravation.

Nghiên Cứu Đặc Điểm Hình Thái Và Một Số Yếu Tố Liên Quan Của Bớt Hori Tại Các Cơ Sở Y Tế Trên Địa Bàn Thành Phố Cần Thơ Năm 2021-2023

“…Nhóm tuổi phổ biến của bớt Hori khác nhau tùy theo nghiên cứu. Cụ thể, nghiên cứu của Xinjun Yang và cộng sự ghi nhận nhóm tuổi 21-29 chiếm tỉ lệ cao nhất với 51,8% [7].…”

“…Trong nghiên cứu của Trần Vũ Linh, 100% mẫu nghiên cứu là nữ [8]. Tương tự, nghiên cứu của Xinjun Yang, nữ giới chiếm tới 98,2% [7]. Như vậy, tỉ lệ mắc bệnh của hai giới còn thay đổi tùy thuộc vào thời điểm và quần thể nghiên cứu, nhưng nhìn chung đây là bệnh hay gặp phổ biến hơn ở phụ nữ, nhất là người châu Á.…”

The role of epidermal growth factor‐containing topical products on recovery and post‐inflammatory hyperpigmentation prevention after laser surgeries: A systematic review and meta‐analysis

“…Laser treatments, such as fractional carbon dioxide (FrCO 2 ) and neodymium yttrium aluminum garnet (QS Nd: YAG) lasers, can cause damage to the basal cell layer, leading to PIH 3 . Studies have found that the incidence of PIH after 532/1064 nm QS Nd: YAG laser surgery ranged from 10% to 50% in Asian patients, 4,5 with FrCO 2 laser showing a higher occurrence rate of 95.8% 6 . Once it occurs, PIH can persist for several months and have psychological impacts on patients 7 .…”