A Retrospective Study of Clinical Profile of Stroke Victims in Coimbatore Medical College Hospital

Kumar, Dr.P Praveen; Devi, Dr.Priyanka; N, Dr.Athmika.

doi:10.9790/0853-1508036770

Cited by 4 publications

(5 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was chosen because it has been demonstrated to be reproducible, experimentally controllable, rapid and relatively easy, affordable, and free of ethical concerns (30). The MTT assay was employed to determine the vitality of cells exposed to test materials since it is the most frequently utilized test because it is a simple and inexpensive method, as many authors have demonstrated (1,2,21,31,32). In the present study, the HGFs were selected for viability assessment as they are dominant resident cells in gingival connective tissue, quickly growing in standard culture medium, and have a high sensitivity in cytotoxicity assays.…”

Section: Discussionmentioning

confidence: 99%

BIOCOMPATIBILITY OF 3D PRINTED PHOTOINITIATED PROSTHODONTIC RESINS (In vitro Study)

Farid,

Abbas,

Mehanna

et al. 2023

Alexandria Dental Journal

View full text Add to dashboard Cite

INTRODUCTION:The production of numerous types of materials for diverse uses in dentistry is a rapidly growing and researchintensive field. Although 3D printed resins are among the many materials utilized in prosthetic appliances today, research on their biocompatibility in long-term dental applications is limited. OBJECTIVE: Evaluation of cellular behavior of human gingival fibroblasts "HGFs" when put in contact with 3D photoinitiated printed resins and heat polymerized acrylic resin. METHODOLOGY: HGFs were isolated from attached keratinized gingival tissues from healthy patients who had crown lengthening procedures, cellular viability using MTT assay in response to 3D printed resin Dental LT Clear (FORM LABS), compared to Heatpolymerized acrylic resin (Acrostone)which was assessed throughout four-time intervals (24, 48, 72 and 168 hours). RESULTS: All groups' cell viability decreased over time, although with favorable cell viability of more than 90% and non-cytotoxicity. It was found to be significant among Heat polymerized acrylic resin (RG), while among Dental LT Clear (TG) the decrease in cell viability were statistically insignificant. The highest cell viability was found after 24 hours among all groups; however, the least viability was found after 48 hours among RG, and among TG after 72 hours. There was a non-statistical significant difference in cell viability after 168 hours. CONCLUSION: Throughout time intervals and for long term use, it was found that photoinitiated resin were less cytotoxic than heat polymerized acrylic resin but with no statistically significant difference.

show abstract

Section: Discussionmentioning

confidence: 99%

BIOCOMPATIBILITY OF 3D PRINTED PHOTOINITIATED PROSTHODONTIC RESINS (In vitro Study)

Farid,

Abbas,

Mehanna

et al. 2023

Alexandria Dental Journal

View full text Add to dashboard Cite

show abstract

“…This resin also shows good aesthetic properties, transparency/translucency, resistance to discoloration over time, and biocompatibility in the long term [46][47][48].…”

Section: Methodsmentioning

confidence: 99%

Design, Stereolithographic 3D Printing, and Characterization of TPMS Scaffolds

Gabrieli,

Wenger,

Mazza

et al. 2024

Materials

View full text Add to dashboard Cite

Anatomical and functional tissue loss is one of the most debilitating problems and involves a great cost to the international health-care sector. In the field of bone tissue, the use of scaffolds to promote tissue regeneration is a topic of great interest. In this study, a combination of additive manufacturing and computational methods led to creating porous scaffolds with complex microstructure and mechanical behavior comparable to those of cancellous bone. Specifically, some representative models of triply periodic minimal surfaces (TPMSs) were 3D-printed through a stereolithographic technique using a dental resin. Schwarz primitive and gyroid surfaces were created computationally: they are characterized by a complex geometry and a high pore interconnectivity, which play a key role in the mechanism of cell proliferation. Several design parameters can be varied in these structures that can affect the performance of the scaffold: for example, the larger the wall thickness, the lower the elastic modulus and compressive strength. Morphological and mechanical analyses were performed to experimentally assess the properties of the scaffolds. The relationship between relative density and elastic modulus has been analyzed by applying different models, and a power-law equation was found suitable to describe the trend in both structures.

show abstract

“…Worldwide, about 20 million people suffer from stroke every year out of this 5 million will die and 15 million will survive, of this 5 million who survived will be paralyzed by the stroke. The Indian National Commission on Macroeconomics and Health has stated that the number of stroke cases increases from 1 million in 2000 to 1.6 million in 2015 [5]. There are certain risk factors that results in the development of stroke.…”

Section: Introductionmentioning

confidence: 99%

“…The score for each ability is a number between 0 and 4, 0 for normal functioning and 4 for completely impaired. The severity of stroke is categorized as no symptoms (0), minor stroke (1-4), moderate (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15), moderate to severe (16)(17)(18)(19)(20), and severe [11]. A clinical pharmacist can play a major role in identification of risk factors and their effects among stroke patients which can be modified by performing patient counseling regarding lifestyle modifications.…”

Section: Introductionmentioning

confidence: 99%

Evaluating Risk Factors, Clinical and Therapeutic Profile of Stroke Patients Presenting to a Tertiary Care Hospital

Lakshmi

Satish

Aswani

et al. 2021

Asian J Pharm Clin Res

View full text Add to dashboard Cite

Objective: According to the World Health Organization, stroke is the second leading cause of death for people above the age of 60 years, and the fifth leading cause in people aged 15–59 years old. This study mainly aims to evaluate the prevalence of risk factors, clinical features, pattern of drugs prescribed, and severity of stroke among patients. Methods: A cross-sectional study was carried out in a tertiary care teaching hospital on 210 patients for a period of 6 months. Patients aged 18 years and above were included in the study. The severity of stroke was assessed using National Institute of Health Stroke Scale (NIHSS). Results: The majority of the patients were under the age group of 61–70 years (31%). The incidence of ischemic stroke (81%) was more common compared to hemorrhagic stroke (19%). Males (66%) are prone to stroke compared to females (34%). The most common risk factor was hyperlipidemia (29%) followed by hypertension (17%). Antihypertensives (28%) were most commonly used drugs followed by antihyperlipidemics (23%). Most of the prescriptions were prescribed with 4–6 drugs per prescription (62%). Moderate stroke (69%) was most commonly observed in patients. A total of 147 drug-drug interactions were observed. Among 147 drug-drug interaction, the most commonly observed drug-drug interaction was aspirin with metformin (15%). Conclusion: The present study emphasizes on the need to identify risk factors and providing awareness among the patients by a pharmacist in minimizing the disease burden. Early identification of risk factors and pattern of therapy based on therapeutic guidelines plays a crucial role in qualitative patient care.

show abstract

A Retrospective Study of Clinical Profile of Stroke Victims in Coimbatore Medical College Hospital

Cited by 4 publications

References 4 publications

BIOCOMPATIBILITY OF 3D PRINTED PHOTOINITIATED PROSTHODONTIC RESINS (In vitro Study)

BIOCOMPATIBILITY OF 3D PRINTED PHOTOINITIATED PROSTHODONTIC RESINS (In vitro Study)

Design, Stereolithographic 3D Printing, and Characterization of TPMS Scaffolds

Evaluating Risk Factors, Clinical and Therapeutic Profile of Stroke Patients Presenting to a Tertiary Care Hospital

Contact Info

Product

Resources

About