A retrospective study of Marjolin′s ulcer over an eleven year period

Challa, Vasu Reddy; Deshmane, Vijayalakshmi; Reddy, Madhusudana Bommasandra Ashwatha

doi:10.4103/0974-2077.146667

Cited by 16 publications

(16 citation statements)

References 20 publications

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“…Squamous cell carcinoma is the most common histological type among these wounds, followed by basal cell carcinoma, sarcoma, and melanoma [2, 10, 11, 16]. The male-to-female ratio increases with increasing patient age over 50 years [10, 11, 16].…”

Section: Discussionmentioning

confidence: 99%

“…The toxins theory, which proposes that the chronic inflammatory processes that lead to tissue damage produce toxins that may be carcinogenic, was proposed by Treves and Pack [11]. Virchow's theory of chronic irritation explains that, with chronic irritation and repeated tissue injury, the epithelium becomes less stable, loses contact inhibition, and undergoes malignant change.…”

Section: Discussionmentioning

confidence: 99%

“…Marjolin's ulcer is also associated with nonhealing wounds, venous ulcers, lupus vulgaris, vaccination scars, snake bite scars, chronic osteomyelitis fistulae [1], amputation stumps, cystostomy sites, chronic lymphedema, chronic pilonidal sinuses [2], pressure ulcers in spina bifida patients [3], ischial bursitis [4], hidradenitis suppurativa [5], posttraumatic scars [6–9], surgical scars [10], and scars after coronary artery bypass grafting [11]. …”

Section: Introductionmentioning

confidence: 99%

“…The most commonly affected sites are the lower extremities, followed by the head and neck region and the trunk [1, 11]. The most commonly involved areas of the head are the scalp [1, 6] and face [1, 10]; in one reported case, the nose was affected [12], and in another, the neck was affected [8].…”

Section: Introductionmentioning

confidence: 99%

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Acute Marjolin’s Ulcer in a Postauricular Scar after Mastoidectomy

Alhysoni

Bukhari

Hajjaj

2016

Case Reports in Otolaryngology

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Background. Marjolin's ulcer is a rare, aggressive cutaneous malignancy that arises primarily in burn scars but can occur in other types of scars. Squamous cell carcinoma is the most common variant, and while malignant degeneration usually takes a long time, it can develop acutely. Case Report. a 30-year-old man who developed Marjolin's ulcer acutely in a right postauricular scar after mastoidectomy and the incision and drainage of a mastoid abscess. To the best of our knowledge, this report is the first to describe a Marjolin's ulcer in a postauricular surgical scar. However, it has been reported in others areas in the head and neck. Conclusion. Marjolin's ulcer is most commonly observed after postburn scars, but it may be observed after any type of scars, as our patient developed an SCC with a postsurgical scar. Early diagnosis is essential, and a biopsy should be performed on any nonhealing wound or chronic wound that undergoes a sudden change. Tissue samples should be taken from both the centre and the margins of the wound.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Acute Marjolin’s Ulcer in a Postauricular Scar after Mastoidectomy

Alhysoni

Bukhari

Hajjaj

2016

Case Reports in Otolaryngology

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“…5 El estudio de diseminación se realiza con imágenes para descartar compromiso óseo local (y diferenciar de osteomielitis) con radiografías, Tomografía computada y/o Resonancia magnética y luego a distancia con Tomografía computada.…”

Section: Figuraunclassified

Ulcera de Marjolin, reporte de caso

Manubens¹,

Utreras²,

Breton³

et al. 2018

Rev. chil. dermatol

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ResumenSe presenta el caso de una mujer de 77 años, sin antecedentes relevantes, con úlcera en tobillo izquierdo de dos años de evolución relacionada a herida previa por quemadura con agua caliente de aproximadamente 60 años de antigüedad, con crecimiento progresivo y mala respuesta a tratamiento inicial con curaciones y luego con antibióticos. Se realiza estudio con biopsia cutánea incisional que confirma cáncer espinocelular moderadamente diferenciado e infiltrante en dermis reticular, lo cual corresponde a una úlcera de Marjolin. Se deriva a cirugía oncológica en donde se realiza el estudio de etapificación con resultado de lesión ósea por contigüidad y una tomografía computada (TC) de tórax, abdomen y pelvis sin diseminación a distancia, por lo que se decide amputación infracondilea de la extremidad afectada. Debido a este caso de interés, se realiza una revisión sobre úlcera de Marjolin, con el fin de lograr un diagnóstico adecuado y un tratamiento precoz.Palabras claves: úlcera de marjolin; carcinoma espinocelular; quemadura; cicatriz. summaRyWe present the case of a 77-year-old woman, with no relevant history, with a left ankle ulcer of two years of evolution related to previous burn injury with hot water of approximately 60 years old, with progressive growth and poor response to initial treatment with cures and then with antibiotics. A study was performed with cutaneous incisional biopsy confirming moderately differentiated and infiltrating squamous cell cancer in the reticular dermis, which corresponds to a Marjolin ulcer. It is derived to oncologic surgery where the etapification study is carried out with result of contiguous bone injury and a computed tomography (CT) thorax, abdomen and pelvis without distant dissemination, so infracondile amputation of the affected extremity is decided. Due to this interest case report, a review of Marjolin's ulcer is performed, in order to achieve an adequate diagnosis and early treatment.Key words: marjolin ulcer; squamous cell carcinoma; burn; scar. S e conoce genéricamente como úlcera de Marjolin a las neoplasias que se originan en procesos cicatriciales o inflamatorios crónicos de la piel, especialmente sobre quemaduras, aunque existen varios reportes sobre úlceras venosas o por decúbito, hidradenitis supurativa, fístulas de osteomielitis, sitios de gastrostomía, entre otras. La neoplasia más frecuentemente originada corresponde al carcinoma espinocelular. Es una entidad reconocida, pero rara. Su tratamiento consiste habitualmente en la cirugía con extirpación completa con már-genes de seguridad asociado a un injerto cutáneo correctivo o amputación en caso de compromiso óseo y/o cutáneo extenso. Casos ClíniCos Ulcera de Marjolin, reporte de casoPresentamos el siguiente caso de interés, donde se logra el diagnóstico definitivo de úlcera de Marjolin tras meses de tratamiento frustro de una úlcera crónica. Se insta a aumentar el grado de sospecha de malignidad en el diagnóstico diferencial de ulceras crónicas, especialmente aquellas relacionadas al antecedente de u...

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Marjolin’s Ulcer

Gore

2023

Uncommon Ulcers of the Extremities

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A retrospective study of Marjolin′s ulcer over an eleven year period

Cited by 16 publications

References 20 publications

Acute Marjolin’s Ulcer in a Postauricular Scar after Mastoidectomy

Acute Marjolin’s Ulcer in a Postauricular Scar after Mastoidectomy

Ulcera de Marjolin, reporte de caso

Marjolin’s Ulcer

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