A retrospective study of the role of the argon laser in the management of epistaxis secondary to hereditary haemorrhagic telangiectasia

Lennox, P.; Harries, Meredydd; Lund, Valerie J.; Howard, David

doi:10.1017/s0022215100136370

Cited by 45 publications

(42 citation statements)

References 7 publications

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“…Among the surgical options is laser coagulation. Several retrospective studies have shown the efficiency of laser treatment for epistaxis in HHT patients [3][4][5]. Especially in mild to moderate cases, the treatment seems to be beneficial [3].…”

Section: Introductionmentioning

confidence: 99%

“…Several retrospective studies have shown the efficiency of laser treatment for epistaxis in HHT patients [3][4][5]. Especially in mild to moderate cases, the treatment seems to be beneficial [3]. Laser coagulation is a noninvasive procedure, which in most cases can be performed in the outpatient clinic under local anesthesia.…”

Section: Introductionmentioning

confidence: 99%

“…However, it is not the treatment of choice for acute ongoing epistaxis. Different methods have been proposed to quantify epistaxis and to assess the efficacy of treatments [3,[6][7][8][9]. At the present time, only very few prospective trials measuring the effect of laser treatment have been performed [9,10].…”

Section: Introductionmentioning

confidence: 99%

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Efficiency of laser treatment in patients with hereditary hemorrhagic telangiectasia

Jørgensen

Lange

Wanscher

et al. 2011

Eur Arch Otorhinolaryngol

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Earlier studies have shown the effect of laser treatment on epistaxis in patients with hereditary hemorrhagic telangiectasia (HHT). At the present time, only very few prospective trials have been performed, and many studies are based on patients' subjective assessment of the severity of epistaxis. This prospective study measures the objective effect of laser treatment in HHT patients with mild to moderate epistaxis. We introduce an objective measure to assess the severity of epistaxis: the bleeding time (BT). Before and after treatment, the quality of life, as measured by the patient, was assessed and compared to normative data. In 30 patients, we measured the BT before laser treatment 1.5 and 6.5 months after treatment. The Short form 36 (SF-36), a validated health questionnaire, was completed before and 6.5 months after treatment. Compared to preoperative value, BT was significantly reduced 1.5 and 6.5 months after laser treatment (p < 0.05) in both cases. No significant difference in quality of life, before and after treatment, was found. The quality of life of the HHT patients was reduced in five out of eight dimensions when compared with the Danish background population. Laser treatment reduces epistaxis in HHT patients with mild to moderate epistaxis for at least 6 months; this group of patients have reduced quality of life compared to the background population.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Efficiency of laser treatment in patients with hereditary hemorrhagic telangiectasia

Jørgensen

Lange

Wanscher

et al. 2011

Eur Arch Otorhinolaryngol

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“…The argon laser has a wavelength of 488/514nm, and the KTP wavelength is 532nm; these are preferentially absorbed by the colour red, so are able to coagulate the individual telangiectasia without full-thickness mucosal injury ( Figure 4) (96,97) . The Nd:YAG laser causes significantly more tissue destruction than argon or KTP and the CO 2 laser is much less helpful with a higher risk of bleeding as it is a 'cutting' rather than 'coagulating' laser.…”

Section: Endonasal Laser Coagulationmentioning

confidence: 99%

“…The reduction in epistaxis severity and frequency after laser are not permanent, as new lesions will inevitably form, but it can be repeated ad infinitum if it is successful. Laser treatment tends to be most successful in patients who report mild to mo- derate epistaxis, and repeated treatments may have an additive effect (96) .…”

Section: Endonasal Laser Coagulationmentioning

confidence: 99%

Hereditary haemorrhagic telangiectasia

Rimmer

Lund

2015

Rhin

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Background: Hereditary haemorrhagic telangiectasia is an autosomal dominant vascular disease characterized by recurrent epistaxis, mucocutaneous telangiectasia and visceral arteriovenous malformations. Methodology:The genetic basis and pathophysiology of the disease are discussed. Diagnostic criteria and the clinical course of the condition are considered. The current management options, both medical and surgical, are reviewed. Conclusions:Hereditary haemorrhagic telangiectasia requires specialist treatment for the problems it causes, and is best managed in specialist centres. Epistaxis is often the major symptom, significantly affecting patients' quality of life. An understanding of the available treatment options is therefore important for the otorhinolaryngologist.

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Office‐based sclerotherapy for recurrent epistaxis due to hereditary hemorrhagic telangiectasia: a pilot study

Boyer

Fernandes

Durán

et al. 2011

Int Forum Allergy Rhinol

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A retrospective study of the role of the argon laser in the management of epistaxis secondary to hereditary haemorrhagic telangiectasia

Cited by 45 publications

References 7 publications

Efficiency of laser treatment in patients with hereditary hemorrhagic telangiectasia

Efficiency of laser treatment in patients with hereditary hemorrhagic telangiectasia

Hereditary haemorrhagic telangiectasia

Office‐based sclerotherapy for recurrent epistaxis due to hereditary hemorrhagic telangiectasia: a pilot study

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