2024
DOI: 10.32394/pe/189711
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A retrospective study to evaluate the safety and efficacy of intrapleural alteplase in pediatric empyema

Majid Keivanfar,
Rasool Kermani,
Mehrdad Hosseinpour
et al.

Abstract: IntroductionMedical treatment of pediatric empyema consists of appropriate antibiotics, chest tube insertion, and intrapleural fibrinolytic drugs to facilitate pleural drainage. There is a lack of consensus about the drug of choice for fibrinolytic therapy, so this study was designed to evaluate the safety and efficacy of intrapleural alteplase in pediatric empyema.Material and MethodsThe medical records of all children with empyema treated with intrapleural alteplase at a university hospital between January 2… Show more

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