A reversible fluorescent probe for monitoring Ag(I) ions

Abstract

Silver-containing nanomaterials are of interest for their antibiotic properties, for a wide range of applications from medicine to consumer products. However, much remains to be learnt about the degradation of such materials and their effects on human health. While most analyses involve measurement of total silver levels, it is important also to be able to measure concentrations of active free Ag(I) ions. We report here the preparation of a coumarin-based probe, thiocoumarin silver sensor 1 (), that responds reversibly to the addition of silver ions through the appearance of a new fluorescence emission peak at 565 nm. Importantly, this peak is not observed in the presence of Hg(II), a common interferent in Ag(I) sensing. To establish the utility of this sensor, we prepared silver-doped phosphate glasses with demonstrated bactericidal properties, and observed the Ag(I) release from these glasses in solutions of different ionic strength. is therefore a useful tool for the study of the environmental and medical effects of silver-containing materials.

Pattern recognition of toxic metal ions using a single-probe thiocoumarin array

“…Thiocoumarins have previously been reported as probes for Hg 2+ , Au 3+ and Ag + . [24][25][26] The fluorescence signalling in each of these reported cases involves an increase in fluorescence due to the induced conversion from the non-fluorescent thiocarbonyl to highly fluorescent carbonyl species upon interaction with the metal ion. This desulfurization phenomenon has been observed for a range of thioketones; thionaphthalimides have been demonstrated to convert to their analogous oxygen counterparts upon treatment with Hg 2+ .…”

Coumarin‐based Chemosensors for Metal Ions Detection

“…Lim et al. reported the preparation of thio‐coumarin silver sensor SC8 , [55] a coumarin‐based probe to examine the release of silver ions from nanomaterials containing silver which reversibly responds to the addition of Ag + ions by forming a fresh fluorescence emission peak at 565 nm. When SC8 was brought to excitation at 470 nm after treatment with AgNO 3 , two emission peaks i. e., 511 nm due to coumarin, a product of desulfurization, and 565 nm due to non‐covalent Ag + association, were detected.…”

Elucidating sensing mechanisms of a pyrene excimer-based calix[4]arene for ratiometric detection of Hg(ii) and Ag(i) and chemosensor behaviour as INHIBITION or IMPLICATION logic gates

“…Screening assays were performed by dissolving 1 and 2 in DMSO (stock solution 25 mM) and stock solutions 25 ) was attempted to be determined by continuous variation method, Job's plot 71,72,86 Equimolar solutions of 2 and each cation were mixed to a standard volume (3 mL) varying the molar ratio but keeping the total concentration of the species constant. These studies were conducted by uorescence spectroscopy with the same experimental conditions described above for chemosensor 2.…”

“…In this context, different techniques for detection of such contaminants have already been reported. 3,[16][17][18][19][20][21][22][23][24][25] Among them, uorescence-based sensors are particularly interesting over other techniques due to their simplicity for implementation, fast response, local observation, selectivity and sensitivity. 1,5 In particular, uorescent ratiometric detection has become one of the most powerful tools for molecular sensing.…”