A Review and Meta-analysis of the Efficacy of Antibiotics and Probiotics in Management of Pouchitis

Nikfar, Shekoufeh; Darvish-Damavandi, Mahnaz; Abdollahi, Mostafa

doi:10.3923/ijp.2010.826.835

Cited by 28 publications

(12 citation statements)

References 29 publications

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“…The included articles covered 5 groups: UC (22/36, 61.1%) [12, 15, 20, 22, 24, 26, 29–39, 42–46], CD (5/36, 13.9%) [14, 16, 18, 21, 23], pouchitis (2/36, 5.6%) [13, 19], UC and CD (5/36, 13.9%) [11, 25, 27, 28, 40], and UC and CD and pouchitis (2/36, 5.6%) [17, 41]. The included 36 articles contained 443 studies, with an average of 12.3 studies per article.…”

Section: Resultsmentioning

confidence: 99%

“…The average AMSTAR score of the included reviews was 5.81 (range 1–10), which indicates moderate quality. According to the AMSTAR scale and the rating system used by the Canadian Agency for Drugs and Technologies in Health (CADTH), only 4 of the MAs/SRs [21–24] were classified as high quality; 24 of the MAs/SRs [11, 13–18, 20, 26, 29–33, 35, 37–41, 43–46] were classified as moderate quality, and the other 8 MAs/SRs [12, 19, 25, 27, 28, 34, 36, 42] were classified as low quality. The most common AMSTAR items in which the reviews lost points were items 1, 4 and 5.…”

Section: Resultsmentioning

confidence: 99%

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Methodological Quality Assessment of Meta-Analyses and Systematic Reviews of Probiotics in Inflammatory Bowel Disease and Pouchitis

et al. 2016

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BackgroundProbiotics are widely used for the induction and maintenance of remission in inflammatory bowel disease (IBD) and pouchitis. There are a large number of meta-analyses (MAs)/ systematic reviews (SRs) on this subject, the methodological quality of which has not been evaluated.ObjectivesThis study aimed to evaluate the methodological quality of and summarize the evidence obtained from MAs/SRs of probiotic treatments for IBD and pouchitis patients.MethodsThe PubMed, EMBASE, Cochrane Library and China National Knowledge Infrastructure (CNKI) databases were searched to identify Chinese and English language MAs/SRs of the use of probiotics for IBD and pouchitis. The Assessment of Multiple Systematic Reviews (AMSTAR) scale was used to assess the methodological quality of the studies.ResultsA total of 36 MAs/SRs were evaluated. The AMSTAR scores of the included studies ranged from 1 to 10, and the average score was 5.81. According to the Canadian Agency for Drugs and Technologies in Health, 4 articles were classified as high quality, 24 articles were classified as moderate quality, and 8 articles were classified as low quality. Most of the MAs/SRs suggested that probiotics had potential benefits for patients with ulcerative colitis (UC), but failed to show effectiveness in the induction and maintenance of remission in Crohn’s disease (CD). The probiotic preparation VSL#3 may play a beneficial role in pouchitis.ConclusionThe overall methodological quality of the current MAs/SRs in the field of probiotics for IBD and pouchitis was found to be low to moderate. More MAs/SRs of high quality are required to support using probiotics to treat IBD and pouchitis.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Methodological Quality Assessment of Meta-Analyses and Systematic Reviews of Probiotics in Inflammatory Bowel Disease and Pouchitis

et al. 2016

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“…Probiotics are effective in ulcerative colitis and their effectiveness in maintaining remission and preventing relapse is com-Asieh Hosseini, Shekoufeh Nikfar, Mohammad Abdollahi parable with mesalazine [13] and only special preparations of probiotics have been suggested to be effective in Crohn's disease (CD) [14]. In agreement with this idea, the benefit of probiotics in the management of pouchitis after ileal pouch anal anastomosis (IPAA) operation was confirmed by metaanalysis [15,16]. It is believed that pouchitis shares many common clinical and histological features with inflammatory bowel disease (IBD) [17].…”

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confidence: 94%

Editorial Are probiotics effective in management of irritable bowel syndrome?

Hosseini¹,

Nikfar²,

Abdollahi³

2012

aoms

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“…our pharmacies are full of these types of drugs as well as nutritional supplements but scientific evidences behind their usage are insufficient yet. Newly, probiotics have been recommended for treating or preventing a wide range of GI disorders including ulcerative colitis [2][3][4], Crohn's disease [5], and irritable bowel syndrome [6]. Probiotics are live microorganisms such as bacteria and yeast.…”

Section: Introductionmentioning

confidence: 99%

A Meta-Analysis and Systematic Review on the Effect of Probiotics in Acute Diarrhea

Salari

Nikfar²,

Abdollahi³

2012

IADT

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A Review and Meta-analysis of the Efficacy of Antibiotics and Probiotics in Management of Pouchitis

Cited by 28 publications

References 29 publications

Methodological Quality Assessment of Meta-Analyses and Systematic Reviews of Probiotics in Inflammatory Bowel Disease and Pouchitis

Methodological Quality Assessment of Meta-Analyses and Systematic Reviews of Probiotics in Inflammatory Bowel Disease and Pouchitis

Editorial Are probiotics effective in management of irritable bowel syndrome?

A Meta-Analysis and Systematic Review on the Effect of Probiotics in Acute Diarrhea

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