A Review and Proposed New Classification of Benign Acquired Neoplasms with Hair Follicle Differentiation

Lb, Rosen

doi:10.1097/00000372-199010000-00011

Cited by 29 publications

(13 citation statements)

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“…4C). All these features correspond to the cellular characteristics of an epithelial sac in a normal follicle in catagen (14,15), (Fig. 4D).…”

Section: Late Stage Of Trichofolliculomasupporting

confidence: 64%

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The trichofolliculoma undergoes changes corresponding to the regressing normal hair follicle in its cycle

Schulz¹,

Hartschuh

1998

J Cutan Pathol

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The trichofolliculoma is a follicularly differentiated hamartoma, usually described as showing many vellus follicles, spreading from a central infundibular cyst. In spite of the well known regressive changes of normal hair follicles during catagen and telogen, the possibility of corresponding changes in the trichofolliculoma has not yet been discussed in the literature. By examining a total of 31 cases of trichofolliculoma it is demonstrated that this hamartoma undergoes an evolutionary process with great morphological changes, which can be attributed to the anagen, catagen, and telogen phase of the follicular cycle.

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“…4C). All these features correspond to the cellular characteristics of an epithelial sac in a normal follicle in catagen (14,15), (Fig. 4D).…”

Section: Late Stage Of Trichofolliculomasupporting

confidence: 64%

“…The diverse histopathologic fmdings were compared \\ith the known morphological features of the anagen. catagen, and telogen phase of a hair follicle (9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20).…”

Section: Methodsmentioning

confidence: 99%

The trichofolliculoma undergoes changes corresponding to the regressing normal hair follicle in its cycle

Schulz¹,

Hartschuh

1998

J Cutan Pathol

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“…However, this tumor appears to belong to the wide spectrum of cutaneous adnexal neoplasms. Electron-microscopic studies were not contributive to sup port an adnexal differentiation [2], In all but 1 case, no sudoral differentiation was identified on histology, but the contiguity of the basaloid proliferation with follicular epi thelium and the presence of occasional isolated sebaceous cells within the tumor lobules [2,3] suggested a pilosebaceous origin; the benign acquired neoplasms with hair fol licle differentiation are a complex group [8], and we unfor tunately lack specific immunomarkers for the pilosebaceous structures. Immunohistochemical studies of the epi thelial component of cutaneous lymphadenoma (table 1) were not conclusive.…”

Section: Discussionmentioning

confidence: 99%

Cutaneous Lymphadenoma Report of 2 Cases

Masouyé¹

1992

Dermatology

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Cutaneous lymphadenoma is a recently described tumor with a distinctive histological picture associating a basaloid epithelial proliferation and intraepithelial lymphocytes; it seems to represent a benign adnexal neoplasm of uncertain histogenesis. We documented 2 additional examples of cutaneous lymphadenoma with typical histological features; the contiguity of some tumor lobules with preexisting follicular structures was noted. In 1 case, a cutaneous osteoma was present below the tumor. On immunostainings, S-100 protein revealed numerous dendritic intraepithelial and stromal cells. The basaloid proliferation was positive for broad-spectrum keratin antibodies, but negative for KL1 antibody. In addition, several areas were positive for involucrin within tumor lobules. Our findings are consistent with a pilosebaceous origin of cutaneous lymphadenoma.

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“…3,4 Three clinical forms of trichoepithelioma are recognized: 5,6 • A small solitary form • A small multiple form which is inherited in an autosomal dominant fashion • A rare giant solitary form.…”

Section: Discussionmentioning

confidence: 99%

Trichoepithelioma

Mosby¹,

Naidu²,

Ranpise³

et al. 2011

JIAOMR

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Trichoepithelioma-a small benign tumor derived from basal cells in the hair follicle. It may occur sporadically or as the cardinal feature of a relatively common genetic disorder called multiple familial trichoepithelioma characterized by the presence of many small tumors predominantly on the face, inherited in an autosomal dominant pattern. A trichoepithelioma can undergo malignant transformation into a basal cell carcinoma. 1 This is a case report of 66-year-old male patient with a rounded and mobile firm swelling of 1 cm on mandibular labial vestibule of the oral cavity causing alarm and discomfort to the patient.

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A Review and Proposed New Classification of Benign Acquired Neoplasms with Hair Follicle Differentiation

Cited by 29 publications

References 0 publications

The trichofolliculoma undergoes changes corresponding to the regressing normal hair follicle in its cycle

The trichofolliculoma undergoes changes corresponding to the regressing normal hair follicle in its cycle

Cutaneous Lymphadenoma Report of 2 Cases

Trichoepithelioma

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