A Review: Aquilaria Species as Potential of Pharmacological

Abstract

One of the plants that is rich in benefits is from the genus Aquilaria spp. which is known to be able to produce agarwood resin. This genus includes 47 species, of which the four main species are Aquilaria malaccensis, Aquilaria subintegra, Aquilaria crassna and Aquilaria sinensis. Aquilaria species are known to have a wide spectrum of pharmacological activity and have been reported in many studies, including activity, anticancer, anti-inflammatory, AChE inhibitor (Acetylcholinesterase), anti-proliferative, and antidiabetic. The aim of this review is to expand information on the pharmacological activity of various Aquilaria species that can support future studies in the medical field of medicine.

Sesquiterpenoids and hexanorcucurbitacin from Aquilaria malaccensis agarwood with anti-inflammatory effects by inhibiting the STAT1/AKT/MAPK/NLRP3 pathway

“…A. malaccensis is used in traditional herbal medicine to relieve epilepsy, rheumatism, inflammation, weakness, bronchitis, and in the treatment of snake bites. 9 And recently, in vivo and in vitro studies reported the phytomedicinal uses of agarwood of anti-inflammatory, immunomodulatory, anti-obesity, antidiabetic activity in asthma, neurological disorders, stress and anxiety reduction, cancer, and others. 10 While A. malaccensis and agarwood have shown potential in various areas of traditional medicine, scientific research is still ongoing to validate these claims and to better understand the specific bioactive compounds responsible for these effects.…”