This chapter observes the implications of climate change on production and yield of crops, and food security (FS) in India as per the previous studies. It also explains that climate change induced pests and insects in the agricultural sector. It also analyzes the role of adaptation and mitigation strategies in the agricultural sector and FS. The yield and production of crops are predicted to decline due to climate change and pests' germination. The use of technologies, mixed cropping pattern, cropping intensity, climate-resilient crops, drought-tolerance crop, irrigation facilities, soil management, water harvesting, bio-technology, green fertilizer, hybrid varieties of seed, soil conservation, crop rotation, appropriate technology, digital technology, ICT, and integrated pest management strategies will be effective for agricultural sustainability and FS in India. It also suggests the scope of further research in the above-mentioned fields.