“…Based on the principles of Persian medicine, Awram and Bothur occur as a result of humoral imbalances and the body inability to eliminate undesirable and unwanted substances through common and logical ways ( 7 ), therefore, accumulated materials are driven out of the body through other ways like the skin, which can cause various skin problems. In this study, the reference books of Persian medicine such as Makhzan ol advieh ( 8 ), Canon of Medicine ( 9 )and Exir-e Azam ( 10 ) were reviewed for recommended drugs to treatment of Awram and Bothur , most of these medications are resolvent ( Mohallil ) and have dissolving property.…”