The medium in the cooling circulation channel of the magnetic drive centrifugal pump will take away the heat generated by the magnetic eddy current and bearing friction in time to avoid the high temperature demagnetization phenomenon of the permanent magnets. Therefore, the reasonable design of the cooling circulation channel directly affects the stable operation of the magnetic drive centrifugal pump. In this paper, the heat exchange and temperature distribution in the cooling circulating channel of magnetic drive pump are studied by means of numerical calculation of fluid-heat coupling and external characteristic test. The temperature distribution and development law of the isolation sleeve clearance, the bottom of the isolation sleeve and the reflow hole are analysed emphatically, and the convection heat transfer coefficient distribution in the isolation sleeve clearance is studied.