2024
DOI: 10.1177/10732748241299072
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A Review of Advances in Mitochondrial Research in Cancer

Zhiru Li,
Wu Zhang,
Shaowei Guo
et al.

Abstract: Background Abnormalities in mitochondrial structure or function are closely related to the development of malignant tumors. Mitochondrial metabolic reprogramming provides precursor substances and energy for the vital activities of tumor cells, so that cancer cells can rapidly adapt to the unfavorable environment of hypoxia and nutrient deficiency. Mitochondria can enable tumor cells to gain the ability to proliferate, escape immune responses, and develop drug resistance by altering constitutive junctions, oxid… Show more

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