2020
DOI: 10.1007/s10067-020-05511-8
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A review of applications of metabolomics in osteoarthritis

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Cited by 30 publications
(17 citation statements)
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“…Arginine has anti-inflammatory and antioxidant properties and is a prerequisite for the syncretization of many molecules [ 26 ]. Arginine can contribute to inflammation-related diseases including osteoarthritis [ 27 ].…”
Section: Discussionmentioning
confidence: 99%
“…Arginine has anti-inflammatory and antioxidant properties and is a prerequisite for the syncretization of many molecules [ 26 ]. Arginine can contribute to inflammation-related diseases including osteoarthritis [ 27 ].…”
Section: Discussionmentioning
confidence: 99%
“…By using an untargeted approach, metabolomics encompasses the study of the most abundant small molecules (metabolites) in whole organisms, tissues, cells, biofluids, and culture media to better understand the metabolic changes occurring during physiological and pathological conditions [21][22][23] . This technique can be applied in a…”
mentioning
confidence: 99%
“…Based on the above information analysis, in the initial stage of ONFH, reduced angiogenesis, insu cient blood supply, hypoxia, metabolic disorders, leading to local osteonecrosis, apoptosis, osteoclastmediated bone resorption [20,32,33] . Then the osteoblast-mediated repair response begins [34,35] .…”
Section: Discussionmentioning
confidence: 99%