A review of aptamer-conjugated nanomaterials for analytical sample preparation: Classification according to the utilized nanomaterials

What is the role of microbial biotechnology and genetic engineering in medicine?

“…Aptamers are single‐stranded oligonucleotides with sizes between 70 and 100 nucleotides that form specific three‐dimensional structures and are capable of recognizing various types of target molecules with high affinity (similar to antibodies). Aptamers are expected to provide superior affinity to antibodies since they can be selected and enhanced with in vitro techniques using a screening method known as SELEX (Uğurlu et al, 2024 ). Therefore, these molecules are being investigated as a real alternative to monoclonal antibodies in biomedical research.…”

Relevant Aspects in the Development of Electrochemical Aptasensors for the Determination of Antibiotics—A Review

“…This binding can be accomplished through electrostatic interaction, hydrogen bonding, or van der Waals force. The structure of aptamers allows them to bind to their targets in a way that provides high affinity and specificity, similar to the specificities of monoclonal antibodies; consequently, aptamers are called chemical antibodies [1][2][3].…”