The concept of a liquid oxygen (LOX)-augmented nuclear thermal rocket (NTR) engine is introduced, and Its potential for revolutionizing lunar space transportation system (L TS) performance using extraterrestrial "lunar-derived" liquid oxygen (LUNOX) is outlined. The L'OX-augmented NTR (LANTR) represents the marriage of conventional liquid hydrogen (LH;0-cooled NTR and airbreathing engine technologies. The large divergent section of the NTR nozzle functions as an "afterburner" into which oxygen is injected and supersonically combusted with nuclear preheated hydrogen emerging from the NTR's choked sonic throat--"scramjet propulsion in reverse." By varying the oxygen~to-fuel mixture ratio (MR), the LANTR concept can provide variable thrust and specific impulse (Isp) capability with a LH 2 -cooled NTR operating at relatively constant power output. For example, at a MR = 3, the thrust per engine can be increased by a factor of 2.75 while the Isp decreases by only 30%. With this thrust augmentation option, smaller "easier to develop" NTRs become more acceptable from a mission performance standpoint (e.g., Earth escape gravity losses are reduced and perigee propulsion requirements are eliminated). Hydrogen mass and volume is also reduced resulting in smaller space vehicles. An evolutionary NTR-based lunar architecture, requiring only Shuttle C and/or "in-line" Shuttle-derived launch vehicles (SDVs), would operate initially in an "expendable mode" with LH 2 -cooled NTA lunar transfer vehicles (L TVs) delivering 80% more payload on