The reasonable expression of live load and its accuracy are important to the safety and design rationality of highway bridge structures. In this study, the optimization issue of the traffic load model for the suspenders of large-scale suspension bridges is studied. Taking a 2300-m main span suspension bridge as an example, a method for suspender classification based on the geometric feature of the influence lines is proposed, and the extreme traffic load effect scenarios are analyzed and used as an optimization reference. Multi-objective optimization based on a genetic algorithm is used to explore the improvement of the traffic load model of the suspender. The traffic load model of the suspender is optimized with three objectives, i.e., accuracy, convenience, and improvement, and the optimization results regarding the load value and loading length are obtained. The value of the uniformly distributed load of the optimized model ranges from 6.4 kN/m to 8.9 kN/m, and the maximum value of the concentrated force could reach 1433 kN. By comparing the obtained optimized model with the current specification model and the extreme load effect scenario model, the improved applicability of the optimized model in the analysis of the load effect of the suspender can be verified. The optimized method and relevant conclusions can provide useful references for the improved design and operation management of similar bridge structures.