A review of diagnosis, etiology, assessment, and management of patients with myocardial infarction in the absence of obstructive coronary artery disease

Sharedalal, Parija; Aronow, Wilbert S.

doi:10.1080/21548331.2020.1817459

Cited by 4 publications

(7 citation statements)

References 84 publications

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“…Reynolds H et al reports MI based on culprit lesion ischemic/vascular cause in 64% observed patients and 21% had an alternate, non-ischemic diagnosis, most commonly myocarditis [ 11 ]. Attending physicians followed recommendations, based on current ESC and AHA guidelines for the right clinical decision in each case [ 12 , 16 , 19 , 22 ].…”

Section: Discussionmentioning

confidence: 99%

Symptomatology, prognosis and clinical findings of STEMI as a ramification of COVID-19: A systematic review and proportion meta-analysis

Jaiswal

Almas

Ang

et al. 2022

Annals of Medicine &Amp; Surgery

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Section: Discussionmentioning

confidence: 99%

Symptomatology, prognosis and clinical findings of STEMI as a ramification of COVID-19: A systematic review and proportion meta-analysis

Jaiswal

Almas

Ang

et al. 2022

Annals of Medicine &Amp; Surgery

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“…As reported in the literature, MINOCA is more frequent in women [16]. Fortunately, cardiologists are more and more aware of this condition, far from benign [17] [18], due to the growing literature in that field [19] [20].…”

Section: Discussionmentioning

confidence: 99%

Sex Differences in Clinical and Angiographic Characteristics in Acute Coronary Syndrome Patients in Dakar, Senegal

Ndao¹,

Ka²,

Mboup³

et al. 2022

WJCD

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Background: Coronary artery disease (CAD) is in relentless progression, along with the adoption of western lifestyle in sub-Saharan Africa. In Senegal, the incidence of acute coronary syndrome (ACS) rose from 5% to 12% in Dakar during the last 20 years. That increase was observed in both women and men, and according to current data, the former paid the heaviest price in terms of mortality compared to men. In this study, we aim to retrospectively assess the clinical characteristics and angiographic profile of ACS in women compared to men in two tertiary care centers in Dakar. Methods: In this study, we retrospectively analyzed and compared data between men and women among 133 patients who underwent coronary angiogram for ACS in 2 tertiary centers from February 2019 to January 2020. Results: A total of 133 patients were included in our study of whom 97 (72.9%) were men. The mean age was 58 ± 13.6 years. Women were older than men (61.4 ± 14.3 years vs 56.6 ± 13.5 years (p = 0.07). Hypertension, sedentary lifestyle and obesity were significantly more frequent in women (69.4%, 52.7% and 19.4%) when compared to men (38.8%, 25.7% and 6.19%) respectively, (p = 0.001; 0.002 and 0.03). Smoking was less frequent in women (2.8%) than in men (44.3%), (p < 0.001). The mean time from diagnosis to coronary angiography was not statistically different regardless of the presentation mode. On coronary angiogram, single vessel disease was most common (36.1% of men vs 33.3% of women) followed by triple vessel disease (24.7% vs 19.4% respectively). The left anterior descending artery was the most commonly affected vessel (84.4% of men vs. 61.1% of women) in both sexes followed by the left circumflex artery. The left main stem was diseased similarly in both sexes (around 8%). The majority of patients had low SYNTAX score but more often women than men (97.2% vs 92.78%, p = 0.04). Among all the patients, 65 (48.9%) underwent PCI with no statistical difference between men and women. Conclusion: In our study,

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“…The presence of MI and lack of obstructive disease on coronary angiography are required for the diagnosis of MINOCA [1]. Approximately 90% of patients with MI have evident coronary artery obstruction (stenosis greater than 50%).…”

Section: Introductionmentioning

confidence: 99%

“…MINOCA is a complex condition with multiple etiologies, including Takotsubo syndrome and coronary artery dissection. There are no angiographic findings of occlusion in the major epicardial vessels in patients with MINOCA; rather, myonecrosis is caused by distal embolization due to plaque rupture [1]. Compensatory expansion of stenotic epicardial vessels as a result of atherosclerosis is frequently a cause of angiographic underestimation, creating the impression of normal or minimally stenotic coronary arteries [8].…”

Section: Introductionmentioning

confidence: 99%

“…Although type 2 myocardial infarction (MI) has been recognized for years, MINOCA (myocardial infarction in the absence of obstructive coronary artery) is a new term. The presence of MI and lack of obstructive disease on coronary angiography are required for the diagnosis of MINOCA 1 . Approximately 90% of patients with MI have evident coronary artery obstruction (stenosis greater than 50%).…”

Section: Introductionmentioning

confidence: 99%

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MINOCA mimic: Type 2 myocardial infarction due to severe aortic stenosis complicated by cardiogenic shock

Islam

Hennawi

Bakir

et al. 2023

gcsp

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Acute myocardial infarction without significant obstructive coronary disease presents a challenging clinical entity that requires timely intervention. The term myocardial infarction with nonobstructive coronary arteries (MINOCA) describes a working diagnosis attributed to varying etiologies in patients with a presumed ischemic cardiac condition. Several overlapping etiologies can be classified as type 2 myocardial infarction (MI). The 2019 AHA statement established diagnostic criteria and clarified the associated confusion, aiding in appropriate diagnosis. In this report, we present a case of demand-ischemia MINOCA and cardiogenic shock in a patient with severe aortic stenosis (AS).

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A review of diagnosis, etiology, assessment, and management of patients with myocardial infarction in the absence of obstructive coronary artery disease

Cited by 4 publications

References 84 publications

Symptomatology, prognosis and clinical findings of STEMI as a ramification of COVID-19: A systematic review and proportion meta-analysis

Symptomatology, prognosis and clinical findings of STEMI as a ramification of COVID-19: A systematic review and proportion meta-analysis

Sex Differences in Clinical and Angiographic Characteristics in Acute Coronary Syndrome Patients in Dakar, Senegal

MINOCA mimic: Type 2 myocardial infarction due to severe aortic stenosis complicated by cardiogenic shock

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