A Review of Digital Health and Biotelemetry: Modern Approaches towards Personalized Medicine and Remote Health Assessment

Busnatu, Ștefan; Niculescu, Adelina-Gabriela; Bolocan, Alexandra; Andronic, Octavian; Stoian, Anca Pantea; Scafa-Udriște, Alexandru; Stănescu, Ana Maria Alexandra; Păduraru, Dan Nicolae; Nicolescu, Mihnea Ioan; Grumezescu, Valentina; Jinga, Viorel

doi:10.3390/jpm12101656

Cited by 17 publications

(7 citation statements)

References 126 publications

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“…All the measures, as well as the associated costs, leave their mark on the economical side of any dental private practice [ 24 ]. The future will be different as well, from a broader integration of biotelemetry [ 25 ] and telemedicine into the public health response (even dentistry—as pointed out in a recent report [ 26 ]) to changes in dental practices and schools of dental medicine worldwide [ 27 ]. One of the easiest elements would be the inclusion of a careful telephone screening for patients before their schedule at a dental clinic, to minimize the risk of spreading (any) transmissible disease [ 28 ], as other medical specialties are also proposing [ 29 ].…”

Section: Discussionmentioning

confidence: 99%

Management of SARS-CoV-2 Prevention Methods in Dental Offices—A Cross-Sectional Study in Bucharest, Romania

Nicolescu,

Lupu,

Georgescu

et al. 2024

Healthcare

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We compared the managing of prevention methods for SARS-CoV-2 infections in dental offices before and immediately after the COVID-19 pandemic. The purpose of this study was to find out the varieties of infection prevention methods used by dentists before and during the pandemic and compare them. We designed a digital transversal questionnaire with 15 closed questions that was sent to 150 dentists in Bucharest, Romania. We received n = 112 valid answers during July-August 2021 from dentists of all age groups (25–60 years), with a sex ratio of 0.36, which agreed to anonymously participate in this study. The results showed an increase in types and amount of personal protection equipment (i.e., ocular/facial protection, supplemental gown, and upgrading the FFP1 masks to FFP2 or FFP3). Ocular protection showed statistical significance by gender but not by age group. Vaccination rate against SARS-CoV-2 was at 80% of the participant dentists at the time of the survey and had statistical significance. However, vaccination status of the patients did not alter dentists’ protection protocol.

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Section: Discussionmentioning

confidence: 99%

Management of SARS-CoV-2 Prevention Methods in Dental Offices—A Cross-Sectional Study in Bucharest, Romania

Nicolescu,

Lupu,

Georgescu

et al. 2024

Healthcare

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“…Clearly, the greatest impact for our device will be among patients undergoing radiation therapy for head and neck carcinomas, by reducing xerostomia and improving their quality of life [ 30 ]. The future of biotelemetry devices will yield an acceleration of diagnosis and disease monitoring, mostly benefiting patients but also medical personnel [ 31 ].…”

Section: Discussionmentioning

confidence: 99%

A New Model of Salivary Pacemaker—A Proof of Concept and First Clinical Use

Funieru,

Tudose,

Dobrică

et al. 2023

Medicina

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Background and Objectives: Saliva is of utmost importance for maintaining oral health. Management of saliva flow rate deficiency recently includes salivary neuro-electrostimulation. The aim of this paper is to present a new model of salivary pacemaker—the MICROSAL device (MD), an intelligent, miniaturized, and implant-supported oral device used for salivary stimulation. Materials and Methods: This report presents the development, calibration, and first clinical tests which involved the MD. The novel features of this device are the pH sensor and the fact that it communicates with the patient’s smartphone, where oral wetness and pH are graphically exposed. Saliva samples were taken before and after the MD was used on a 68-year-old patient suffering from post-irradiation xerostomia, and albumin and total protein were analyzed. Results: The device uses up to 3 V and time intervals of 2 s seconds for stimulation. The total volume of all saliva samples collected during the clinical trial was almost seven times higher after the device was used. Albumin decreased from a maximum of 0.15 g/dL to 0.04 g/dL, and total proteins from 0.65 g/dL to 0.21 g/dL, after salivary stimulation. Conclusions: The MD increased saliva secretion of the patient, and we are confident it will be a good solution for future management of salivary gland hypofunction.

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“…To accelerate the advancement of clinical trials, digital technologies can be involved. Specifically, they can be leveraged to enhance participants' access and engagement, reducing associated costs, and minimizing study complexity [143][144][145][146]. Moreover, significant data amounts are being gathered during clinical trials, such as demographic data, patient data collected from sensors and wearable devices, patient-reported outcomes, etc.…”

Section: Conclusion and Future Perspectivesmentioning

confidence: 99%

The State of the Art of Pediatric Multiple Sclerosis

Teleanu

Niculescu

Vladâcenco

et al. 2023

IJMS

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Multiple sclerosis (MS) represents a chronic immune-mediated neurodegenerative disease of the central nervous system that generally debuts around the age of 20–30 years. Still, in recent years, MS has been increasingly recognized among the pediatric population, being characterized by several peculiar features compared to adult-onset disease. Unfortunately, the etiology and disease mechanisms are poorly understood, rendering the already limited MS treatment options with uncertain efficacy and safety in pediatric patients. Thus, this review aims to shed some light on the progress in MS therapeutic strategies specifically addressed to children and adolescents. In this regard, the present paper briefly discusses the etiology, risk factors, comorbidities, and diagnosis possibilities for pediatric-onset MS (POMS), further moving to a detailed presentation of current treatment strategies, recent clinical trials, and emerging alternatives. Particularly, promising care solutions are indicated, including new treatment formulations, stem cell therapies, and cognitive training methods.

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A Review of Digital Health and Biotelemetry: Modern Approaches towards Personalized Medicine and Remote Health Assessment

Cited by 17 publications

References 126 publications

Management of SARS-CoV-2 Prevention Methods in Dental Offices—A Cross-Sectional Study in Bucharest, Romania

Management of SARS-CoV-2 Prevention Methods in Dental Offices—A Cross-Sectional Study in Bucharest, Romania

A New Model of Salivary Pacemaker—A Proof of Concept and First Clinical Use

The State of the Art of Pediatric Multiple Sclerosis

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