Thermotropic nematic LCs can modulate light in phases, amplitudes, and polarizations [1]. Many photonic applications based LCs have developed, such as displays, electro-optical switches, lenses, optical vortex generators, variable optical attenuations, solar cells and so on. Thermotropic nematic LCs have great potential in bio-medical applications. In this session, we mainly introduce two the bio-medical applications based on thermotropic nematic LCs: biosensors and ophthalmic lenses. In biosensors, the key is interfacial interactions between biosamples and LC molecules. We will introduce a LC and polymer complex system, the LC and polymer composite film (LCPCF), whose surface free energy is electrically switchable. LCPCF can help to test the sperm quality and high-density-lipoprotein (HDL). In ophthalmic applications, we will introduce the challenges and requirements for design of ophthalmic lenses. A polarizer-free LC lens with large aperture size is also introduced.
Biosensors Using Nematic Liquid CrystalsIn general, interfacial interactions between LCs and bio-samples (or sensing targets) are the key to design a biosensor using nematic LCs [2][3][4][5][6][7]. Such an interfacial interaction often causes the re-orientations of LC molecules at the interface. As a result, optical properties of LC change and the change of the orientation of LC can be read out by observing under a polarizing microscopy. LC can optically amplify the biological binding events and help us to study the biology. The main approach is to immobilize thermotropic nematic LC onto a solid surface as a sensing interface for bio-samples. 5CB is a commonly used a LC material for biosensing. In the literatures, 5CB has been proved for sensing many bio-samples,