This work studies a series of factors influencing erosion-corrosion in oilfield gathering pipelines steel using the home-made testing pipe flow loop. Results showed that steel was corroded in oil-water flow. The corrosion rate increased with the flow velocity on the whole, and the addition of solid particles would intensify the localized corrosion. For the erosion-corrosion test added with 2 wt% quartz sand at the velocity of 2 m/s, the portion of pure corrosion and pure erosion accounted for 47.50% and 70.83%, respectively. The erosion-enhanced corrosion was 16.67% of the total weight loss, while the corrosion inhibiting the damage from erosion accounted for 35.00%, so negative synergistic effects appeared in the oil-water-sand multiphase flow conditions.