A review of ethnopharmacology of the commonly used antimalarial herbal agents for traditional medicine practice in Ethiopia

Abstract

Malaria is one of the parasitic infections that cause enormous public health, economic, and emotional burden in many tropical and subtropical countries of the world. Resistance of the vector mosquitoes to the current insecticides as well as the emergence of multidrug resistance by malaria parasite to widely used antimalarial drugs has made malaria control and treatment much more difficult. New alternative antimalarial drugs and approaches for mosquito control are urgently required. Ethiopia, as most of the African continent countries, is rich in a wide range of tropical habitats, remarkable biodiversity, and the uses of traditional medicines for treatment of various illnesses. The article thus focuses on review of ethnopharmacological activities (medicinal properties), phytochemistry, and safety (toxicity) of some of the commonly used antimalarial herbal agents in Ethiopia and around which could have significant potential for antimalarial drug discovery and development.

Phytochemical Investigation and Antioxidant Activity of Root Extract of <i>Aloe gilbertii Reynolds</i>, from Konso, Southern Ethiopia

“…The reducing power of each fraction was determined according to a literature procedure [26] Variable concentrations of the different fractions 2.5 mL (0.2-1mg/mL) were mixed with sodium phosphate buffer (2.5 mL, 0.2 M, pH 6.6) and potassium ferricyanide (2.5 mL, 1.0%). The mixtures were incubated at 50°C for 20 min.…”

Traditional Medicine Practice in the Context of COVID-19 Pandemic: Community Claim in Jimma Zone, Oromia, Ethiopia

“…The questionnaires were adapted from previous studies conducted to assess community claims for other types of infections and modified as required. [22][23][24]27,28 The questionnaires were prepared in English. To check the clarity and reliability of the questionnaire, a pretest was conducted on 5% of the sample size.…”

Old and Recent Advances in Life Cycle, Pathogenesis, Diagnosis, Prevention, and Treatment of Malaria Including Perspectives in Ethiopia

“…In developing countries, 80% of the people almost exclusively use TMs. Virtually, 80% of the population living in Ethiopia is dependent on traditional medicine which essentially involves the use of plants [159,160].…”